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artelastin

prenylated flavone from Artocarpus; structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        artelastin: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        artelastin: 1

Experts

1.	Bronze-da-Rocha, Elsa: 1 article (06/2005)
2.	Cidade, Honorina: 1 article (06/2005)
3.	Ferreira, Maria Manuel: 1 article (06/2005)
4.	Kijjoa, Anake: 1 article (06/2005)
5.	Nascimento, Maria São José: 1 article (06/2005)
6.	Pedro, Madalena: 1 article (06/2005)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 06/03/2005 - "Studies to elucidate the basis of the growth inhibitory activity of artelastin were performed in the MCF-7 human breast cancer cell line (GI50 = 6.0 microM). " 06/03/2005 - "Artelastin is a cytotoxic prenylated flavone that disturbs microtubules and interferes with DNA replication in MCF-7 human breast cancer cells."
2.	Neoplasms (Cancer) 06/03/2005 - "Artelastin, a novel prenylated flavone, previously isolated from the wood bark of Artocarpus elasticus, was evaluated for its capacity to inhibit the growth of fifty-two human tumor cell lines, representing nine different tumor types. "

Related Drugs and Biologics

1.	flavone