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tricarbonylchloro(glycinato)ruthenium(II)

a cardioprotective agent; structure in first source

Also Known As:

CO-releasing molecule-3; CORM-3 cpd

Networked: 9 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - tricarbonylchloro(glycinato)ruthenium(II): 9

Experts

1.	Motterlini, Roberto: 4 articles (01/2012 - 05/2004)
2.	Bolli, Roberto: 3 articles (01/2012 - 05/2004)
3.	Dawn, Buddhadeb: 3 articles (01/2012 - 05/2004)
4.	Guo, Yiru: 3 articles (01/2012 - 05/2004)
5.	Stein, Adam B: 3 articles (01/2012 - 05/2004)
6.	Cepinskas, Gediminas: 2 articles (01/2017 - 11/2014)
7.	Tan, Wei: 2 articles (01/2005 - 05/2004)
8.	Wu, Wen-Jian: 2 articles (01/2005 - 05/2004)
9.	Zhu, Xiaoping: 2 articles (01/2005 - 05/2004)
10.	Chen, Gang: 1 article (10/2022)

Related Diseases

1.	Myocardial Infarction 01/01/2005 - "The goal of the present study was to determine whether a water-soluble CORM, tricarbonylchloro(glycinato)ruthenium(II) (CORM-3), induces delayed protection against myocardial infarction 24 h later and to explore the duration of this protection. " 01/01/2012 - "Using a water-soluble CO-releasing molecule (CORM) tricarbonylchloro(glycinato)ruthenium(II) (CORM-3), we previously reported that CO induces a delayed protection against myocardial infarction similar to that observed in the late phase of ischemic preconditioning (PC). "
2.	Sepsis (Septicemia) 01/01/2017 - "The aim of this study was to assess the effects/mechanisms of CO-releasing molecule-3 (CORM-3)-dependent modulation of the NLRP3 inflammasome in cardiac fibroblasts (CF) and its effect on myocardial function in sepsis. "
3.	Periodontal Diseases (Periodontal Disease) 10/05/2015 - "This study was performed to analyze the effect of carbon monoxide (CO)-releasing molecule-3 (CORM-3) in alleviating the production of proinflammatory mediators in macrophages treated with lipopolysaccharide (LPS) from Prevotella intermedia, a pathogen associated with periodontal disease, and its possible mechanisms of action. "
4.	Infarction (Infarctions) 05/01/2004 - "The goal of the present study was to test whether a water-soluble CO-releasing molecule, tricarbonylchloro(glycinato) ruthenium (II) (CORM-3), reduces infarct size in vivo when given in a clinically relevant manner, i.e., at the time of reperfusion. "
5.	Stroke (Strokes) 10/01/2022 - "Both low-dose CO inhalation and CO-releasing molecule-3 (a molecule that emits CO) treatment have shown the benefits of stroke, and perhaps the role of CO in stroke is one of the key areas for future research."

Related Drugs and Biologics

1.	Carbon Monoxide
2.	Inflammasomes
3.	Lipopolysaccharides
4.	Hemin (Panhematin)
5.	Heme (Haem)
6.	Creatinine
7.	tricarbonyldichlororuthenium (II) dimer

Related Therapies and Procedures

1.	Stents