z-Val-Ala-Asp(Ome)-fluoromethylketone

confuse with Z-VAD-FMK

Also Known As:

butyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone; butyloxycarbonyl-valyl-alanyl-aspartyl-O-methyl-fluoromethyl ketone; z-VAD(OMe)-fmk; z-Val-Ala-Asp(Ome)-FMK; zVAD(OMe) peptide

Networked: 5 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Amino Acid Chloromethyl Ketones
    - z-Val-Ala-Asp(Ome)-fluoromethylketone: 5

Experts

1.	Chen, Xiaoting: 1 article (04/2021)
2.	Deng, Zhendong: 1 article (04/2021)
3.	Huang, Lanlan: 1 article (04/2021)
4.	Jin, Dadi: 1 article (04/2021)
5.	Li, Fuxiang: 1 article (04/2021)
6.	Li, Qingchu: 1 article (04/2021)
7.	Lin, Haiyingjie: 1 article (04/2021)
8.	Lin, Shaoqiang: 1 article (04/2021)
9.	Song, Yuwei: 1 article (04/2021)
10.	Yang, Tingting: 1 article (04/2021)

Related Diseases

1.	Lung Injury 03/01/2015 - "The aim of this study was to determine the effect of the broad caspase inhibitor Z-VAD(OMe)-FMK (zVAD) on inflammation and lung injury in a mouse pneumovirus model for severe RSV disease. "
2.	Hearing Loss (Hearing Impairment) 01/01/2008 - "In the present study, we analyzed the effect of the pan-caspase inhibitor z-Val-Ala-Asp(Ome)-fluoromethylketone (Z-VAD-FMK) on 3-NP-induced hearing loss in a model showing temporary threshold shifts at low frequencies and permanent threshold shifts at high frequencies. "
3.	Inflammation (Inflammations) 03/01/2015 - "The aim of this study was to determine the effect of the broad caspase inhibitor Z-VAD(OMe)-FMK (zVAD) on inflammation and lung injury in a mouse pneumovirus model for severe RSV disease. "
4.	Thyroid Neoplasms (Thyroid Cancer) 06/01/2003 - "The caspase inhibitor Z-Val-Ala-Asp-(OMe)-fluoromethylketone protected thyroid cancer cells from BS-RNase-induced apoptosis. "
5.	Osteosarcoma (Osteogenic Sarcoma) 04/01/2021 - "EF24 significantly induced cell death in osteosarcoma cell lines, and this effect was significantly reversed by ferrostatin-1, but not Z-VAD(Ome)-FMK, MRT68921 or necrosulfonamide. "

Related Drugs and Biologics

1.	Caspases
2.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone
3.	ferrostatin-1
4.	N- (4- (N- (3- methoxypyrazin- 2- yl)sulfamoyl)phenyl)- 3- (5- nitrothiophene- 2- yl)acrylamide
5.	erucylphosphocholine
6.	ribonuclease SPL