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2- demethoxycarbonyl- 2- ethoxycarbonyl- 11- deoxymisoprostol

a gastroprotective agent

Also Known As:

11-deoxymisoprostol

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Makara, N S: 5 articles (03/2008 - 01/2003)
2.	Baschenko, N Zh: 4 articles (03/2008 - 10/2006)
3.	Nazarov, V S: 4 articles (03/2008 - 10/2006)
4.	Ivanova, N A: 4 articles (02/2008 - 01/2003)
5.	Sapozhnikova, T A: 4 articles (02/2008 - 01/2003)
6.	Gabdrakhmanova, S F: 3 articles (03/2008 - 10/2006)
7.	Zarudiĭ, F S: 3 articles (03/2008 - 01/2003)
8.	Khisamutdinova, R Yu: 2 articles (02/2008 - 10/2006)
9.	Zarudii, F S: 2 articles (02/2008 - 10/2006)
10.	Khisamutdinova, R Iu: 2 articles (07/2007 - 01/2003)

Related Diseases

1.	Chemical and Drug Induced Liver Injury 02/01/2008 - "Therapeutic administration of 11-deoxymisoprostol had a hepatoprotective effect, which manifested in a decrease in the content of alanine transaminase and aspartate transaminase in blood plasma, and produced a choleretic effect in rats with CCI4-induced toxic hepatitis." 07/01/2007 - "2-Demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol (11-DMP) produces antioxidant effect on the models of toxic hepatitis induced by paracetamol and carbon tetrachloride. "
2.	Ulcer 10/01/2006 - "11-Deoxymisoprostol (prostaglandin E1 analog) exhibited a pronounced gastroprotective effect on various models of experimental ulcers induced by nonsteroid antiinflammatory drugs. " 01/01/2003 - "11-Deoxymisoprostol showed gastroprotector activity on the acute models of ulcers induced by acetylsalicylic acid and ethanol and produced curative effect on the chronic ulceration model induced by acetic acid. "
3.	Thrombosis (Thrombus) 03/01/2008 - "11-Deoxymisoprostol demonstrates antiaggregant properties with respect to the adrenalin-, collagen-, and ADP-induced aggregation of thrombocytes, which is manifested by a decrease in the rate of blood platelet agglutination and their secretion, and by an increase in the time of thrombus formation."
4.	Peptic Ulcer (Peptic Ulcers) 10/01/2006 - "Gastroprotective properties of 11-deoxymisoprostol (prostaglandin E1 analog) and its effect on the level of sialic acids in gastric tissue of rats with peptic ulcer."
5.	Hepatitis 02/01/2008 - "Choleretic activity of 2-demethoxycarbonyl-2-ethoxycarbonyl-11-deoxymisoprostol on the model of CCl4-induced hepatitis."

Related Drugs and Biologics

1.	Acetic Acid (Vinegar)
2.	Sialic Acids
3.	Formaldehyde (Formol)
4.	Collagen
5.	Carrageenan
6.	Carbon Tetrachloride (Tetrachloromethane)
7.	Aspirin (Acetylsalicylic Acid)
8.	Aspartate Aminotransferases (Aspartate Transaminase)
9.	Antioxidants
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