V-Set Domain-Containing T-Cell Activation Inhibitor 1

A B7 antigen subtype that inhibits the costimulation of T-cell activation, proliferation, cytokine production and development of cytotoxicity. The over expression of this protein in a variety of tumor cell types suggests its role in TUMOR IMMUNE EVASION.

Also Known As:

B7H4 Immune Costimulatory Protein; Immune Costimulatory Protein B7-H4; T-Cell Costimulatory Molecule B7x; Immune Costimulatory Protein B7 H4; T Cell Costimulatory Molecule B7x; V Set Domain Containing T Cell Activation Inhibitor 1

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intercellular Signaling Peptides and Proteins: 29768
    - B7 Antigens: 157
      - V-Set Domain-Containing T-Cell Activation Inhibitor 1: 1
  - Membrane Proteins: 10078
    - B7 Antigens: 157
      - V-Set Domain-Containing T-Cell Activation Inhibitor 1: 1
Biological Factors: 2472
- Antigens: 143924
  - Surface Antigens: 5813
    - B7 Antigens: 157
      - V-Set Domain-Containing T-Cell Activation Inhibitor 1: 1
- Intercellular Signaling Peptides and Proteins: 29768
  - B7 Antigens: 157
    - V-Set Domain-Containing T-Cell Activation Inhibitor 1: 1

mouse Vtcn1 protein

Bio-Agent Context: Research Results