muraymycin A1

a uridyl peptide; muraymycins have a core skeleton consisting of an unusual nucleotide disaccharide and a lipophilic derivative of glycine linked to a unique dipeptide urea; inhibits MraY synthesis of peptidoglycan; in vitro activity against Gram-positive bacteria; found in Streptomyces; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Barbieri, Laurel R: 1 article (09/2002)
2.	Carter, Guy T: 1 article (09/2002)
3.	Lenoy, Eileen: 1 article (09/2002)
4.	Lotvin, Jason: 1 article (09/2002)
5.	McDonald, Leonard A: 1 article (09/2002)
6.	Petersen, Peter J: 1 article (09/2002)
7.	Siegel, Marshall M: 1 article (09/2002)
8.	Singh, Guy: 1 article (09/2002)
9.	Williamson, R Thomas: 1 article (09/2002)

Related Diseases

1.	Staphylococcal Infections 09/04/2002 - "One of the most active compounds, muraymycin A1, demonstrated protection in vivo against Staphylococcus aureus infection in mice (ED50 1.1 mg/kg)."