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octyl caffeate

an antioxidant; structure in first source

Also Known As:

octylcaffeate

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Cinnamates: 48
      - Caffeic Acids: 15
        octyl caffeate: 3

Experts

1.	Ishikawa, Masaaki: 1 article (12/2005)
2.	Kanno, Syu-ichi: 1 article (12/2005)
3.	Kimura, Katsuhiko: 1 article (12/2005)
4.	Koiwai, Kimiko: 1 article (12/2005)
5.	Ohtake, Takaharu: 1 article (12/2005)
6.	Osanai, Yu: 1 article (12/2005)
7.	Takeshita, Mitsuhiro: 1 article (12/2005)
8.	Ujibe, Mayuko: 1 article (12/2005)
9.	Uwai, Kohji: 1 article (12/2005)
10.	Banskota, Arjun H: 1 article (05/2003)

Related Diseases

1.	Endotoxemia 04/15/2003 - "In conclusion, we demonstrate that a novel potent antioxidant, octyl caffeate, significantly ameliorates circulatory failure of endotoxemia in vivo by a mechanism involving suppression of iNOS expression through inactivation of mitogen-activated protein kinases in RASMCs."
2.	Shock 04/15/2003 - "In conclusion, we demonstrate that a novel potent antioxidant, octyl caffeate, significantly ameliorates circulatory failure of endotoxemia in vivo by a mechanism involving suppression of iNOS expression through inactivation of mitogen-activated protein kinases in RASMCs."
3.	Neoplasms (Cancer) 05/01/2003 - "Besides CAPE, 4-phenylbutyl caffeate, 8-phenyl-7-octenyl caffeate, 2-cyclohexylethyl caffeate and n-octyl caffeate at an oral dose of 2 mg/mice/d caused a 55%, 43%, 55% and 35% reduction of the tumor nodules in their lung metastasis formation, respectively. "
4.	Neoplasm Metastasis (Metastasis) 05/01/2003 - "Besides CAPE, 4-phenylbutyl caffeate, 8-phenyl-7-octenyl caffeate, 2-cyclohexylethyl caffeate and n-octyl caffeate at an oral dose of 2 mg/mice/d caused a 55%, 43%, 55% and 35% reduction of the tumor nodules in their lung metastasis formation, respectively. "
5.	Lymphoma (Lymphomas) 12/01/2005 - "We found that octylcaffeate, a semisynthetic caffeic acid derivative, strongly inhibited the growth of human histiolytic lymphoma U937 cells in a dose- and time-dependent manner via apoptosis. "

Related Drugs and Biologics

1.	Mitogen-Activated Protein Kinases
2.	Antioxidants
3.	caffeic acid