adamanolol

structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 04/30/2003 - "The druglike molecule we named adamanolol competitively inhibited the interaction between the two cancer-linked nuclear proteins, ESX (an epithelial-specific transcription factor) and Sur-2/DRIP130 (a Ras-linked subunit of the human mediator complex), which is important for the overexpression of Her2 gene in malignant breast cancer cells. "
2.	Breast Neoplasms (Breast Cancer) 04/30/2003 - "Adamanolol impaired Her2 expression and caused cell death selectively in Her2-positive breast cancer cells. " 04/30/2003 - "The druglike molecule we named adamanolol competitively inhibited the interaction between the two cancer-linked nuclear proteins, ESX (an epithelial-specific transcription factor) and Sur-2/DRIP130 (a Ras-linked subunit of the human mediator complex), which is important for the overexpression of Her2 gene in malignant breast cancer cells. "

1.	Mediator Complex
2.	Transcription Factors (Transcription Factor)
3.	Nuclear Proteins (Protein, Nuclear)