HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

Chir 98014

structure in first source

Also Known As:

Chir-98014; Chir98014

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aminopyridines: 77
    - Chir 98014: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Chir 98014: 2
  - Pyridines: 88
    - Aminopyridines: 77
      - Chir 98014: 2

Experts

1.	Gdowicz-Kłosok, Agnieszka: 1 article (10/2021)
2.	Głowala-Kosińska, Magdalena: 1 article (10/2021)
3.	Krześniak, Małgorzata: 1 article (10/2021)
4.	Małachowska, Beata: 1 article (10/2021)
5.	Rusin, Marek: 1 article (10/2021)
6.	Zajkowicz, Artur: 1 article (10/2021)
7.	Łasut-Szyszka, Barbara: 1 article (10/2021)
8.	Das, Jayanta: 1 article (08/2020)
9.	Mathuram, Theodore Lemuel: 1 article (08/2020)
10.	Natarajan, Umamaheswari: 1 article (08/2020)

Related Diseases

1.	Lung Neoplasms (Lung Cancer) 08/01/2020 - "BIO and CHIR 98014 successfully induced apoptosis at lower concentrations in H1975 cells but not in H460 lung cancer cells. " 08/01/2020 - "The apoptotic effect of GSK-3 inhibitors: BIO and CHIR 98014 on H1975 lung cancer cells through ROS generation and mitochondrial dysfunction." 08/01/2020 - "The study elucidates the possible mechanism involved in the ability of GSK-3 inhibitors: BIO and CHIR 98014 to regulate proteins involved in cell death of H1975 lung cancer cells. "
2.	Mitochondrial Diseases (Mitochondrial Disease) 08/01/2020 - "The apoptotic effect of GSK-3 inhibitors: BIO and CHIR 98014 on H1975 lung cancer cells through ROS generation and mitochondrial dysfunction."
3.	Alzheimer Disease (Alzheimer's Disease) 10/14/2021 - "Previously we reported that CHIR-98014 (GSK-3 kinase inhibitor), acting in cells exposed to A + N, prevents activation of TREM2-an innate immunity and p53-regulated gene associated with Alzheimer's disease. "

Related Drugs and Biologics

1.	Glycogen Synthase Kinase 3
2.	Proteins (Proteins, Gene)
3.	Phosphotransferases (Kinase)