Cladosporium herbarum HCh-1 protein

105 amino acids, MW 10.5 kDa, shows the classical signature of members of the hydrophobin family; the recombinant protein was able to bind IgE from six patients sensitized to fungi in vitro, two of those patients were also included in a skin prick test survey and showed strong type I skin reactions to HCh-1, demonstrating the allergenic nature of C. herbarum hydrophobin and indicating a prevalence of sensitization in the range of 8-9%; amino acid sequence in first source
Also Known As:
HCh-1 protein, Cladosporium herbarum; HCh-1 hydrophobin, C herbarum
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Bio-Agent Context: Research Results