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albuferon
to improve the pharmacokinetics of IFN-alpha and decrease dosing frequency, IFN-alpha was fused to human serum albumin producing albuferon
Also Known As:
albuferon-alpha
Networked:
2
relevant articles (
0
outcomes,
2
trials/studies)
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Albumins: 31532
Serum Albumin: 9893
Human Serum Albumin: 2275
albuferon: 2
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Interferons: 39171
Interferon Type I: 4788
Interferon-alpha: 11740
albuferon: 2
Blood Proteins: 12459
Serum Albumin: 9893
Human Serum Albumin: 2275
albuferon: 2
Peptides: 82426
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Interferons: 39171
Interferon Type I: 4788
Interferon-alpha: 11740
albuferon: 2
Biological Factors: 2472
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Interferons: 39171
Interferon Type I: 4788
Interferon-alpha: 11740
albuferon: 2
Experts
1.
Kratz, Felix
: 1 article (12/2008)
2.
Chemmanur, Annie T
: 1 article (08/2006)
3.
Wu, George Y
: 1 article (08/2006)
Related Diseases
1.
Infections
08/01/2006 - "
By May 2004, phase II clinical trials of Albuferon in HCV infection were underway.
"
08/01/2006 - "
Human Genome Sciences Inc (HGS), in collaboration with Novartis AG, is developing Albuferon-alpha, a long-acting injectable human interferon alpha2b fusion protein, for the potential treatment of hepatitis C virus (HCV) infection.
"
2.
Hepatitis C
12/18/2008 - "
Furthermore, Albuferon, a fusion protein of albumin and interferon, is currently being assessed in phase III clinical trials for the treatment of hepatitis C and could become an alternative to pegylated interferon.
"
3.
Neoplasms (Cancer)
08/01/2006 - "
Albuferon also has the potential to treat a broad range of cancers.
"
Related Drugs and Biologics
1.
Proteins (Proteins, Gene)
2.
Interferons
3.
Albumins
Related Therapies and Procedures
1.
Injections