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cycloviolacin O2

macrocyclic peptide (cyclotide) from the two violets, Viola arvensis Murr. and Viola odorata (Violaceae); amino acid sequence in first source

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - Cyclotides: 54
      - cycloviolacin O2: 4

Experts

1.	Craik, David J: 2 articles (01/2020 - 09/2014)
2.	Huang, Yen-Hua: 2 articles (01/2020 - 09/2014)
3.	Göransson, Ulf: 2 articles (09/2013 - 09/2012)
4.	Chan, Lai Y: 1 article (01/2020)
5.	Dang, Tien T: 1 article (01/2020)
6.	Huynh, Tien: 1 article (01/2020)
7.	Kaas, Quentin: 1 article (01/2020)
8.	Nguyen, Linh T T: 1 article (01/2020)
9.	Chaousis, Stephanie: 1 article (09/2014)
10.	Troeira Henriques, Sónia: 1 article (09/2014)

Related Diseases

1.	Infections 09/01/2013 - "Cycloviolacin O2 (CyO2) suppresses productive infection and augments the antiviral efficacy of nelfinavir in HIV-1 infected monocytic cells."
2.	Lymphoma (Lymphomas) 09/18/2012 - "The current study determined the possible DNA-damaging effects of three cyclotides, i.e., cycloviolacin O2, vaby D, and kalata B1, in human lymphoma cells by use of the alkaline version of the comet assay. "
3.	Neoplasms (Cancer) 01/01/2020 - "Because cycloviolacin O2 has previously been shown to have potent activity against a wide range of cancer cell lines including HeLa (human cervical cancer cells) and PC-3 (human prostate cancer cells), the cancer cytotoxicity of the cyclotides isolated from V. arcuata was assessed. " 09/05/2014 - "A novel set of analogues of kalata B1 (the prototypic cyclotide) and kalata B2 and cycloviolacin O2 were examined for their membrane-binding affinity and selectivity towards cancer cells. "
4.	Prostatic Neoplasms (Prostate Cancer) 01/01/2020 - "Because cycloviolacin O2 has previously been shown to have potent activity against a wide range of cancer cell lines including HeLa (human cervical cancer cells) and PC-3 (human prostate cancer cells), the cancer cytotoxicity of the cyclotides isolated from V. arcuata was assessed. "
5.	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/01/2020 - "Because cycloviolacin O2 has previously been shown to have potent activity against a wide range of cancer cell lines including HeLa (human cervical cancer cells) and PC-3 (human prostate cancer cells), the cancer cytotoxicity of the cyclotides isolated from V. arcuata was assessed. "

Related Drugs and Biologics

1.	Nelfinavir (Viracept)
2.	Antiviral Agents (Antivirals)
3.	Cyclotides
4.	kalata B1
5.	DNA (Deoxyribonucleic Acid)
6.	vaby D
7.	kalata B2