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RSD992
structure in first source
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Piperazines: 26
RSD992: 1
Experts
1.
Goldin, Alan L
: 1 article (07/2002)
2.
Hayes, Eric S
: 1 article (07/2002)
3.
Pugsley, Michael K
: 1 article (07/2002)
4.
Walker, Michael J A
: 1 article (07/2002)
Related Diseases
1.
Ventricular Fibrillation
07/01/2002 - "
RSD992 (2-32 micromolkg(-1)min(-1)) increased threshold current (I(T)) for induction of extra-systoles and induction of sustained ventricular fibrillation (VF(T)) and also increased the effective refractory period (ERP) and decreased the maximum following frequency (MFF) in rat and guinea pig hearts.
"
2.
Bradycardia
07/01/2002 - "
Bolus doses (4-128 micromolkg(-1)) and infusions (2-32 micromolkg(-1)min(-1)) of the novel arylpiperazine drug RSD992 produced bradycardia in rats and guinea pigs but had minimal effect on ECG variables.
"