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tribulosin
from Tribulus terrestris (Zygophyllaceae); structure in first source
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Cholestanes
Sterols: 2245
Phytosterols: 1069
Sitosterols: 5
tribulosin: 2
Cholestenes
Sitosterols: 5
tribulosin: 2
Lipids: 114793
Membrane Lipids: 1591
Sterols: 2245
Phytosterols: 1069
Sitosterols: 5
tribulosin: 2
Biological Factors: 2472
Phytochemicals: 5771
Phytosterols: 1069
Sitosterols: 5
tribulosin: 2
Experts
1.
Li, Hong
: 2 articles (12/2011 - 06/2010)
2.
Zhang, Shuang
: 2 articles (12/2011 - 06/2010)
3.
Yang, Shi-Jie
: 1 article (12/2011)
4.
Yang, Shi-jie
: 1 article (06/2010)
Related Diseases
1.
Reperfusion Injury
06/01/2010 - "
Tribulosin protects myocardium against ischemia/reperfusion injury through PKCepsilon activation.
"
06/01/2010 - "
Tribulosin protects rat hearts from ischemia/reperfusion injury.
"
06/01/2010 - "
To investigate the protective effect of tribulosin, a monomer of the gross saponins from Tribulus terrestris, against cardiac ischemia/reperfusion injury and the underlying mechanism in rats.
"
2.
Ischemia
06/01/2010 - "
The hearts were assigned to seven groups: control, ischemia/reperfusion (I/R), treatment with gross saponins from Tribulus terrestris (GSTT) 100 mg/L, treatment with tribulosin (100, 10, and 1 nmol/L) and treatment with a PKC inhibitor (chelerythrine) (1 micromol/L).
"
3.
Infarction (Infarctions)
06/01/2010 - "
GSTT and various concentrations of tribulosin treatment decreased the infarct size to 24.33%, 20.24%, 23.19%, and 30.32% (P<0.01).
"
4.
Hypoxia (Hypoxemia)
12/01/2011 - "
Tribulosin suppresses apoptosis via PKC epsilon and ERK1/2 signaling pathway during hypoxia/reoxygenation in neonatal rat ventricular cardiac myocytes.
"
Related Drugs and Biologics
1.
Protein Kinase C-epsilon
2.
Saponins
3.
chelerythrine