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DPC 602

Also Known As:

DPC-602; DPC602

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - DPC 602: 1

Experts

1.	Bernard, Roberta: 1 article (02/2003)
2.	Bozarth, Tracy A: 1 article (02/2003)
3.	Chopp, Michael: 1 article (02/2003)
4.	Feuerstein, Giora Z: 1 article (02/2003)
5.	Friedman, Steven M: 1 article (02/2003)
6.	Galemmo, Robert A: 1 article (02/2003)
7.	Grzanna, Reinhard: 1 article (02/2003)
8.	Knabb, Robert M: 1 article (02/2003)
9.	Luettgen, Joseph M: 1 article (02/2003)
10.	Vargas, Hugo: 1 article (02/2003)

Related Diseases

1.	Stroke (Strokes) 02/01/2003 - "In the present study we describe the effect of a novel, potent, and selective FXa inhibitor, DPC602, on brain damage and neurobehavioral consequence in a rat thromboembolic model of stroke. " 02/01/2003 - "Laser-Doppler monitoring of cerebral blood flow demonstrated that DPC602 (8 mg/kg, single IV/IP bolus pretreatment) markedly improved cerebral blood flow after thromboembolic stroke by 25% to 160% (n=6; P<0.001) at 1 to 6 hours. "
2.	Infarction (Infarctions) 02/01/2003 - "DPC602 demonstrated concentration- and time-dependent reductions in infarct size, with maximal effect (89% reduction; n=14; P<0.001) at the highest dose over controls. "
3.	Cerebral Hemorrhage 02/01/2003 - "DPC602 treatment did not cause cerebral hemorrhage, assessed by free hemoglobin in the ischemic brain tissues. "

Related Drugs and Biologics

1.	Hemoglobins (Hemoglobin)

Related Therapies and Procedures

1.	Lasers (Laser)