human inv(16) fusion protein

associates with corepressors via a smooth muscle myosin heavy-chain domain; inversion(16) is one of the most frequent chromosomal translocations found in acute myeloid leukemia (AML), occurring in over 8% of AML cases; this translocation results in a protein product that fuses the first 165 amino acids of core binding factor beta to the coiled-coil region of a smooth muscle myosin heavy chain (CBFbeta/SMMHC)

Also Known As:

inv(16) fusion protein, human; inversion (16) fusion protein, human

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Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Mutant Proteins: 1299
    - Mutant Chimeric Proteins
      - Fusion Oncogene Proteins
        human inv(16) fusion protein
  - Neoplasm Proteins: 2
    - Oncogene Proteins: 7793
      - Fusion Oncogene Proteins
        human inv(16) fusion protein