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human inv(16) fusion protein

associates with corepressors via a smooth muscle myosin heavy-chain domain; inversion(16) is one of the most frequent chromosomal translocations found in acute myeloid leukemia (AML), occurring in over 8% of AML cases; this translocation results in a protein product that fuses the first 165 amino acids of core binding factor beta to the coiled-coil region of a smooth muscle myosin heavy chain (CBFbeta/SMMHC)
Also Known As:
inv(16) fusion protein, human; inversion (16) fusion protein, human
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