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wilforol A

from Tripterygium wilfordii; structure in first source

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - wilforol A: 1

Related Diseases

1.

Glioma (Gliomas)

02/16/2023 - "To study the anti-proliferation activity of wilforol A against glioma cells and its possible molecular mechanisms. "
02/16/2023 - "The expression of PI3K and p-Akt genes in the PI3K/AKT pathways were significantly downregulated in glioma cells treated with wilforol A. "
02/16/2023 - "Wilforol A inhibits human glioma cell proliferation and deactivates the PI3K/AKT signaling pathway."
02/16/2023 - "Wilforol A inhibits the growth of glioma cells, reduces the levels of proteins in the P13K/Akt signal transduction pathways and increases the levels of pro-apoptotic proteins."
02/16/2023 - "Elevated levels of pro-apoptotic proteins p53, Bax and cleaved caspase 3 and reduced level of the anti-apoptotic protein Bcl-2 were observed in glioma cells exposed to wilforol A. "

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