|1.||Paterson, Ian: 8 articles (09/2013 - 12/2005)|
|2.||Gardner, Nicola M: 5 articles (09/2013 - 01/2007)|
|3.||Wright, Amy E: 5 articles (01/2010 - 05/2007)|
|4.||Guzmán, Esther: 3 articles (01/2010 - 12/2008)|
|5.||Vogt, Andreas: 2 articles (06/2011 - 11/2005)|
|6.||Balachandran, Raghavan: 2 articles (06/2011 - 11/2005)|
|7.||Day, Billy W: 2 articles (06/2011 - 11/2005)|
|8.||Curran, Dennis P: 2 articles (06/2011 - 11/2005)|
|9.||Naylor, Guy J: 2 articles (01/2010 - 10/2008)|
|10.||Trojanowski, John Q: 1 article (09/2013)|
06/01/2011 - "The natural product (--)-dictyostatin is a microtubule-stabilizing agent that potently inhibits the growth of human cancer cells, including paclitaxel-resistant clones. "
12/01/2008 - "By exploiting a Still-Gennari olefination of a common C11-C26 aldehyde with a C4-C10 or C1-C10 beta-ketophosphonate, three modified C2-C6 region analogues of the 22-membered macrolide dictyostatin were synthesised and evaluated in vitro for growth inhibition against a range of human cancer cell lines, including the Taxol-resistant NCI/ADR-Res cell line. "
01/07/2007 - "A 22-membered macrocyclic discodermolide/dictyostatin hybrid has been designed and synthesised; biological evaluation against a range of human cancer cell lines revealed significant levels of growth inhibition."
03/15/2009 - "By exploiting a Still-Gennari HWE coupling with a common C11-C26 aldehyde, a series of C2-C6 modified analogues of the microtubule-stabilising marine natural product dictyostatin were synthesised and evaluated in vitro for growth inhibition against a range of human cancer cell lines, including the (P-glycoprotein efflux-mediated) Taxol-resistant NCI/ADR cell line. "
10/14/2008 - "A potent dictyostatin-discodermolide hybrid was designed and synthesised; it showed enhanced cell growth inhibitory activity relative to discodermolide in four human cancer cell lines including the Taxol-resistant NCI/ADR-Res cell line."
11/15/2005 - "Like discodermolide, dictyostatin retained antiproliferative activity against human ovarian carcinoma cells resistant to paclitaxel due to beta-tubulin mutations and caused conversion of cellular soluble tubulin pools to microtubules. "
12/01/2005 - "The binding constants of epothilones, eleutherobin, discodermolide, sarcodictyins, 3,17beta-diacetoxy-2-ethoxy-6-oxo-B-homo-estra-1,3,5(10)-triene, and dictyostatin to the paclitaxel site; the critical concentrations of ligand-induced assembly; and their cytotoxicity in carcinoma cells have been measured, and correlations between these parameters have been determined. "
|4.||Breast Neoplasms (Breast Cancer)
|1.||Heterologous Transplantation (Xenotransplantation)