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human APH-1 protein

a presenilin- and nicastrin-binding protein that is needed for intramembrane proteolysis of amyloid-beta precursor and Notch; amino acid sequence in first source
Also Known As:
APH-1 protein, human; Anterior-pharynx-defective protein 1, human; Gamma-secretase subunit aph-1 protein, human; Pen-1 protein, human; Presenilin enhancer protein 1, human
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