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8- cyclopenta- 3- (3- fluoropropyl)- 1- propylxanthine

an A1 adenosine receptor antagonist; structure in first source

Also Known As:

(18F)CPFPX; CPFPX cpd

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Xanthines: 123
    - 8-cyclopenta-3-(3-fluoropropyl)-1-propylxanthine: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purinones: 2
        Xanthines: 123
        8-cyclopenta-3-(3-fluoropropyl)-1-propylxanthine: 3

Experts

1.	Bauer, Andreas: 2 articles (01/2017 - 02/2007)
2.	Elmenhorst, David: 2 articles (01/2017 - 02/2007)
3.	Matusch, Andreas: 2 articles (01/2017 - 02/2007)
4.	Ardaya, María: 1 article (01/2021)
5.	Cavaliere, Fabio: 1 article (01/2021)
6.	Cossío, Unai: 1 article (01/2021)
7.	Domercq, María: 1 article (01/2021)
8.	Garbizu, Maider: 1 article (01/2021)
9.	Gutiérrez, Juan José: 1 article (01/2021)
10.	Gómez-Vallejo, Vanessa: 1 article (01/2021)

Related Diseases

1.	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/01/2021 - "Methods: In this study, the expression of A1ARs after transient middle cerebral artery occlusion (MCAO) was evaluated by positron emission tomography (PET) with [18F]CPFPX and immunohistochemistry (IHC). "
2.	Sleep Deprivation 01/01/2017 - "[18F]CPFPX positron emission tomography was used to quantify A1AR availability in 15 healthy male adults after 52 h of sleep deprivation and following 14 h of recovery sleep. " 02/28/2007 - "We used the highly selective A1 adenosine receptor (A1AR) radioligand [18F]CPFPX ([18F]8-cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine) and quantitative positron emission tomography to assess cerebral A1ARs before and after sleep deprivation in 12 healthy volunteers and a control group (n = 10) with regular sleep. "
3.	Brain Ischemia (Cerebral Ischemia) 01/01/2021 - "Results: In the ischemic territory, [18F]CPFPX signal and IHC showed the overexpression of A1ARs in microglia and infiltrated leukocytes after cerebral ischemia. "

Related Drugs and Biologics

1.	Purinergic P1 Receptors (Adenosine Receptor)