|1.||Szliszka, Ewelina: 2 articles (01/2012 - 01/2009)|
|2.||Czuba, Zenon P: 2 articles (01/2012 - 01/2009)|
|3.||Suzuki, Takashi: 2 articles (10/2007 - 01/2006)|
|4.||Kimura, Yumiko: 2 articles (10/2007 - 01/2006)|
|5.||Akihisa, Toshihiro: 2 articles (10/2007 - 01/2006)|
|6.||Kapche, Gilbert Deccaux W F: 1 article (11/2015)|
|7.||Kuete, Victor: 1 article (11/2015)|
|8.||Zeino, Maen: 1 article (11/2015)|
|9.||Fozing, Christian D: 1 article (11/2015)|
|10.||Efferth, Thomas: 1 article (11/2015)|
08/28/2010 - "Abrogation of Akt signaling by Isobavachalcone contributes to its anti-proliferative effects towards human cancer cells."
11/15/2015 - "Cytotoxicity of three naturally occurring flavonoid derived compounds (artocarpesin, cycloartocarpesin and isobavachalcone) towards multi-factorial drug-resistant cancer cells."
08/28/2010 - "Herein, we report that Isobavachalcone (IBC), a natural chalcone, potently abrogates Akt signaling and exerts anti-proliferative effects on several human cancer cell lines. "
01/01/2006 - "Further, isobavachalcone (4) exhibited inhibitory effects on skin tumor promotion in an in vivo two-stage mouse skin carcinogenesis test using 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter."
11/15/2015 - "In the present study, we investigated the cytotoxicity of three naturally occurring flavonoids including two flavones artocarpesin (1) and cycloartocarpesin (2) and one chalcone, isobavachalcone (3) against 9 drug-sensitive and MDR cancer cell lines. "
01/01/2013 - "The present study investigated the effect of isobavachalcone (IBC), a natural chalcone component of Angelica keiskei, on inflammation by modulating iNOS expression induced by TLR agonists in murine macrophages. "
05/05/2015 - "Taken together, our data suggest that isobavachalcone inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cell by blocking TLR4 signaling and thus, has the potential to ameliorate neuronal injury in brain diseases associated with inflammation."
|3.||Prostatic Neoplasms (Prostate Cancer)
|4.||Neurodegenerative Diseases (Neurodegenerative Disease)
10/01/2007 - "Therefore, isobavachalcone may be applicable as an efficacious and safe drug for the treatment of neuroblastoma."
10/01/2007 - "These results suggest that isobavachalcone induces apoptotic cell death in neuroblastoma via the mitochondrial pathway and has no cytotoxicity against normal cells. "
10/01/2007 - "Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma."
10/01/2007 - "Western blot analysis showed that isobavachalcone significantly reduced pro-caspase-3 and pro-caspase-9, and subsequently increased the level of cleaved caspase-3 and cleaved caspase-9 in both neuroblastoma cell lines. "
10/01/2007 - "All chalcones exhibited cytotoxicity against neuroblastoma cells, and two of them (isobavachalcone and xanthoangelol H) had no effect on normal cells even at high concentration (10(-4) M) exposure. "
|10.||Caspase 3 (Caspase-3)