isobavachin

01/01/2023 - "Our previous study firstly screened out a natural product Isobavachin as anti-hyperuricemia targeted hURAT1 from a Chinese medicine Haitongpi (Cortex Erythrinae). "
01/01/2023 - "Finally, the compound-target-pathway-disease network was constructed by Cytoscape and the mechanism of isobavachin anti-hyperuricemia was discussed based on the network analysis. "
01/01/2023 - "Mechanism of anti-hyperuricemia of isobavachin based on network pharmacology and molecular docking."
12/01/2021 - "Taken together, isobavachin is a promising candidate for the treatment of hyperuricemia and gout."
01/01/2023 - "In view of Isobavachin's diverse pharmacological activities, similar to the Tranilast (as another hURAT1 inhibitor), our study focused on its potential targets and molecular mechanisms of Isobavachin anti-hyperuricemia based on network pharmacology and molecular docking. "

06/01/2023 - "Isobavachin can limit the proliferation of prostate cancer cells by inducing a distinct G1 cell-cycle arrest. "
01/01/2023 - "Based on the simulation results, Isobavachin, IsoMod4, and IsoMod7 were concluded to be stable and exhibited potential properties for developing a novel drug to combat prostate cancer and its associated drug-resistance.Communicated"
01/01/2023 - "Computational approaches for evaluation of isobavachin as potential inhibitor against t877a and w741l mutations in prostate cancer."

12/01/2020 - "Isobavachin is a phenolic with anti-osteoporosis activity. "
06/01/2023 - "A total of 59 chemical components were identified from Jinwugutong Capsules, among which coryfolin, 8-prenylnaringenin, demethoxycurcumin, isobavachin, and genistein may be the main active components of Jinwugutong Capsules in treating osteoporosis. "

01/01/2007 - "Antioxidative as well as cytotoxic effects of the prenylated flavonoids licoflavone C (8-prenylapigenin) and isobavachin (8-prenylliquiritigenin) were investigated in comparison to the corresponding non-prenylated flavonoids (apigenin, liquiritigenin) and vitexin (apigenin-C8-glucoside) using metabolically active H4IIE hepatoma and metabolically poorly active C6 glioma cells. "

12/01/2021 - "Taken together, isobavachin is a promising candidate for the treatment of hyperuricemia and gout."