bavachinin

do not confuse with bavachin

Also Known As:

(2S)-2,3-dihydro-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one; 4'-hydroxy-7-methoxy-6-(3-methyl-2-butenyl)flavanone; 7-O-methylbavachin; bavachinin A

Networked: 21 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        bavachinin: 21
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        bavachinin: 21

Experts

1.	Chen, Xi: 3 articles (10/2018 - 11/2013)
2.	Hong, Zhangyong: 3 articles (10/2018 - 11/2013)
3.	Aali, Ehsan: 2 articles (11/2021 - 01/2019)
4.	Darzi, Sina: 2 articles (11/2021 - 01/2019)
5.	Elahian, Fatemeh: 2 articles (11/2021 - 01/2019)
6.	Mirzaei, Seyed Abbas: 2 articles (11/2021 - 01/2019)
7.	Peymani, Amir: 2 articles (11/2021 - 01/2019)
8.	Rahmani, Babak: 2 articles (11/2021 - 01/2019)
9.	Shirian, Sadegh: 2 articles (11/2021 - 01/2019)
10.	Flavell, Richard: 2 articles (04/2014 - 11/2013)

Related Diseases

1.	Inflammation (Inflammations) 11/01/2013 - "Treatment of allergic inflammation and hyperresponsiveness by a simple compound, Bavachinin, isolated from Chinese herbs." 10/01/2023 - "Bavachinin Ameliorates Rheumatoid Arthritis Inflammation via PPARG/PI3K/AKT Signaling Pathway." 08/25/2021 - "Bavachinin, which is an active flavanone of Proralea corylifolia L., possesses anti-inflammation, anti-angiogenesis, and anti-cancer activities. "
2.	Rheumatoid Arthritis 10/01/2023 - "Bavachinin Ameliorates Rheumatoid Arthritis Inflammation via PPARG/PI3K/AKT Signaling Pathway."
3.	Neoplasms (Cancer) 08/25/2021 - "The present study's aim was to evaluate the anti-cancer activity of bavachinin on NSCLC, and its regulating molecular mechanisms. " 09/15/2012 - "In vivo studies showed that injecting Bavachinin thrice weekly for four weeks significantly reduced tumor volume and CD31 expression in nude mice with KB xenografts. " 06/09/2021 - "Bavachinin induces SCLC apoptosis via intrinsic and extrinsic pathways and causes cancer cell cycle arrest via the ATM/ATR signaling pathway." 06/09/2021 - "Following the administration of bavachinin to xenograft mice with SCLC, the tumor burden decreased without impairing hematologic or hepatorenal functions. " 09/15/2012 - "These data indicate that Bavachinin could be used as a therapeutic agent for inhibiting tumor angiogenesis."
4.	Asthma (Bronchial Asthma) 10/01/2018 - "This system has the potential to be used for the oral delivery of bavachinin to treat asthma and may have potential for the oral delivery of other drugs that have limited pharmacokinetic efficacy." 04/01/2014 - "Bavachinin, which can be isolated from the Chinese herb Fructus Psoraleae, has the potential as a potent anti-asthma drug. " 10/01/2018 - "Here, we fabricated a nanoparticle delivery system for the oral administration of bavachinin to treat asthma, with the aim of solving its administration problem. " 01/01/2021 - "Bavachinin has a good effect in the treatment of mouse asthma models, and it can effectively inhibit the expression of a variety of cytokines. " 10/01/2018 - "Recently, it was found that bavachinin, an essential small molecule in Psoralea corylifolia, has very efficient therapeutic function in asthma treatment in a murine model via the selective inhibition of Th2 cytokine production. "
5.	Non-alcoholic Fatty Liver Disease 02/16/2023 - "Bavachinin (BVC) is proven to possess liver-protecting effect against NAFLD, but its mechanism is still blurry. " 02/16/2023 - "Bavachinin protects the liver in NAFLD by promoting regeneration via targeting PCNA." 11/01/2020 - "The data presented here suggest that bavachinin acts as a cholesterol synthesis enzyme inhibitor, and might serve as a drug for treating NAFLD in the future."

Related Drugs and Biologics

1.	Cytokines
2.	tephrosin
3.	flavanone
4.	Peroxisome Proliferator-Activated Receptors (PPAR)
5.	Therapeutic Uses
6.	Proliferating Cell Nuclear Antigen (PCNA)
7.	Triazoles
8.	Messenger RNA (mRNA)
9.	Oximes
10.	Mitoxantrone (Novantrone)

Related Therapies and Procedures

1.	Oral Administration