|1.||Kumar, Vikash: 1 article (08/2015)|
|2.||Datta, Dipak: 1 article (08/2015)|
|3.||Meena, Sanjeev: 1 article (08/2015)|
|4.||Shaw, Arun K: 1 article (08/2015)|
|5.||Das, Pintu: 1 article (08/2015)|
|6.||Kundooru, Somireddy: 1 article (08/2015)|
|7.||Siddiqi, Mohammad Imran: 1 article (08/2015)|
|8.||Xu, Jin-Mei: 1 article (06/2014)|
|9.||Shi, Xiao-Jing: 1 article (06/2014)|
|10.||Liu, Hong-Min: 1 article (06/2014)|
08/14/2015 - "The application of this study has been shown by utilizing one of the THFs 4a as a key intermediate to complete the total synthesis of marine anti-cancer natural product 2-epi jaspine B."
12/01/2012 - "Pachastrissamine (PA) exhibits cytotoxic activity and promotes apoptosis in several cancer cells. "
06/10/2014 - "Among them, compound 14h showed excellent inhibition against MCF-7 (IC50 = 1.93 μM) and was more potent than 5-Fu and Jaspine B against all three cancer cell lines. "
|2.||Melanoma (Melanoma, Malignant)
12/01/2012 - "Pachastrissamine from Pachastrissa sp. inhibits melanoma cell growth by dual inhibition of Cdk2 and ERK-mediated FOXO3 downregulation."
09/01/2009 - "Altogether, Jaspine B is able to kill melanoma cells by acting on SMS activity and consequently on ceramide formation, and may represent a new class of cytotoxic compounds with potential applications in anticancer melanoma therapy."
09/01/2009 - "Jaspine B was able to dose- and time-dependently decrease the viability of murine B16 and human SK-Mel28 melanoma cells. "
09/01/2009 - "The natural marine anhydrophytosphingosine, Jaspine B, induces apoptosis in melanoma cells by interfering with ceramide metabolism."
01/20/2006 - "[reaction: see text] The natural product pachastrissamine, an anhydrophytosphingosine derivative isolated from various sponges and endowed with cytotoxic activity against several human carcinoma cell lines, was synthesized in three steps and with 72% overall yield from d-ribo-phytosphingosine."