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EN 3231

Also Known As:

EN-3231; EN3231; Morphidex

Networked: 5 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Galer, Bradley S: 1 article (06/2005)
2.	Lee, David: 1 article (06/2005)
3.	Ma, Tina: 1 article (06/2005)
4.	Nagle, Barbara: 1 article (06/2005)
5.	Schlagheck, Thomas G: 1 article (06/2005)
6.	Monck, Nat: 1 article (03/2002)
7.	Caruso, F S: 1 article (01/2000)
8.	Chevlen, E: 1 article (01/2000)
9.	Katz, N P: 1 article (01/2000)

Related Diseases

1.	Chronic Pain 01/01/2000 - "MorphiDex (MS:DM) double-blind, multiple-dose studies in chronic pain patients." 01/01/2000 - "To determine the appropriate conversion regimens from other oral or transdermal opioid analgesics to MorphiDex (MS:DM), 592 patients with moderate to severe chronic pain requiring daily use of opioid analgesics were enrolled in this multicenter, open-label study. " 03/01/2002 - "Endo (which acquired Algos in July 2000) has developed EN-3231, a combination of morphine and dextromethorphan, for the treatment of moderate-to-severe chronic pain. " 06/01/2005 - "MorphiDex (morphine sulfate/dextromethorphan hydrobromide combination) in the treatment of chronic pain: three multicenter, randomized, double-blind, controlled clinical trials fail to demonstrate enhanced opioid analgesia or reduction in tolerance."
2.	Postoperative Pain 01/01/2000 - "MorphiDex pharmacokinetic studies and single-dose analgesic efficacy studies in patients with postoperative pain."
3.	Pain (Aches) 01/01/2000 - "MorphiDex, a 1:1 combination of dextromethorphan and morphine, provides satisfactory pain control at a significantly lower morphine daily dose. " 01/01/2000 - "MorphiDex (MS:DM), a 1:1 (weight:weight) ratio of morphine sulfate (MS) to dextromethorphan hydrobromide (DM), is under clinical development for the treatment of moderate to severe pain. "

Related Drugs and Biologics

1.	Opioid Analgesics (Opioids)
2.	Morphine (MS Contin)
3.	Dextromethorphan (Racemethorphan)
4.	Analgesics (Analgesic Drugs)

Related Therapies and Procedures

1.	Analgesia