|1.||Sandborn, William J: 18 articles (08/2015 - 02/2003)|
|2.||Schreiber, Stefan: 12 articles (11/2011 - 09/2005)|
|3.||Strand, Vibeke: 10 articles (01/2015 - 11/2008)|
|4.||van der Heijde, Désirée: 9 articles (01/2016 - 07/2012)|
|5.||Rutgeerts, Paul: 9 articles (04/2013 - 09/2005)|
|6.||van der Heijde, D: 8 articles (11/2015 - 06/2009)|
|7.||Coteur, G: 8 articles (11/2015 - 06/2009)|
|8.||Colombel, Jean-Frédéric: 8 articles (10/2015 - 06/2008)|
|9.||Coteur, Geoffroy: 8 articles (01/2015 - 01/2009)|
|10.||Combe, Bernard: 8 articles (12/2014 - 11/2008)|
|1.||Crohn Disease (Crohn's Disease)
03/15/2009 - "Three trials, enrolling a total of 1040 patients, are included in the meta-analysis to evaluate the short-term efficacy of certolizumab, which is effective for rapid induction and long-term maintenance of clinical response or remission and can improve quality of life in patients with Crohn's disease. "
07/19/2007 - "In patients with moderate-to-severe Crohn's disease, induction and maintenance therapy with certolizumab pegol was associated with a modest improvement in response rates, as compared with placebo, but with no significant improvement in remission rates. "
10/01/2014 - "Certolizumab pegol was well tolerated in the long-term treatment of Crohn's disease, with sustained remission in some patients continuing in the study for up to 7 years. "
07/19/2007 - "Patients with moderate-to-severe Crohn's disease who had a response to induction therapy with 400 mg of certolizumab pegol were more likely to have a maintained response and a remission at 26 weeks with continued certolizumab pegol treatment than with a switch to placebo. "
08/01/2009 - "Clinically meaningful improvement in health-related quality of life in a randomized controlled trial of certolizumab pegol maintenance therapy for Crohn's disease."
06/01/2011 - "Rapid improvement in the signs and symptoms of rheumatoid arthritis following certolizumab pegol treatment predicts better longterm outcomes: post-hoc analysis of a randomized controlled trial."
10/01/2002 - "Efficacy of a novel PEGylated humanized anti-TNF fragment (CDP870) in patients with rheumatoid arthritis: a phase II double-blinded, randomized, dose-escalating trial."
01/01/2011 - "The construct validity and reliability of the SIAQ were tested in patients with rheumatoid arthritis who volunteered to inject certolizumab pegol using a standard syringe during an open-label multinational extension trial of the long-term safety and efficacy of this drug. "
01/01/2009 - "In patients with active rheumatoid arthritis who had previously failed to respond to treatment with > or = 1 disease-modifying anti-rheumatic drug, certolizumab pegol 400 mg every 4 weeks as monotherapy effectively improved ACR responses at all measured timepoints up to 24 weeks, according to data from the randomized, phase III FAST4WARD trial. "
12/01/2015 - "The aim of the Patient/Physician Reported Efficacy Determination In Clinical Practice Trial (PREDICT; ClinicalTrials identifier NCT01255761) was to compare the patient-reported Routine Assessment of Patient Index Data 3 (RAPID-3) instrument with the investigator-based Clinical Disease Activity Index (CDAI) for assessing certolizumab pegol (CZP) treatment response in rheumatoid arthritis patients at 12 weeks and to predict the treatment response at week 52 using the data from week 12 (coprimary end points). "
04/01/2014 - "Certolizumab pegol is the only PEGylated anti-tumour necrosis factor (TNF)-α agent. "
07/01/2012 - "Certolizumab pegol (CZP) is a PEGylated antitumour necrosis factor agent. "
06/01/2009 - "Certolizumab pegol is a PEGylated tumour necrosis factor inhibitor. "
12/01/2004 - "CDP870 is a PEGylated Fab' fragment of a humanized monoclonal antibody that neutralizes tumour necrosis factor-alpha. "
01/01/2015 - "Previous reports of RAPID-PsA (NCT01087788) demonstrated efficacy and safety of certolizumab pegol (CZP) over 24 weeks in patients with psoriatic arthritis (PsA), including patients with prior antitumour necrosis factor (TNF) therapy. "
01/01/2015 - "Improvements in productivity at paid work and within the household, and increased participation in daily activities after 24 weeks of certolizumab pegol treatment of patients with psoriatic arthritis: results of a phase 3 double-blind randomised placebo-controlled study."
01/01/2014 - "The 216-week RAPID-psoriatic arthritis (PsA) (NCT01087788) trial of certolizumab pegol (CZP) in patients with active PsA was double-blind and placebo-controlled until week 24. "
01/01/2014 - "Effect of different imputation approaches on the evaluation of radiographic progression in patients with psoriatic arthritis: results of the RAPID-PsA 24-week phase III double-blind randomised placebo-controlled study of certolizumab pegol."
01/01/2014 - "To evaluate the efficacy and safety of certolizumab pegol (CZP) after 24 weeks in RAPID-PsA (NCT01087788), an ongoing Phase 3 trial in patients with psoriatic arthritis (PsA). "
01/01/2014 - "Effect of certolizumab pegol on signs and symptoms in patients with psoriatic arthritis: 24-week results of a Phase 3 double-blind randomised placebo-controlled study (RAPID-PsA)."
|5.||Psoriasis (Pustulosis Palmaris et Plantaris)
07/01/2012 - "Successful treatment of moderate to severe plaque psoriasis with the PEGylated Fab' certolizumab pegol: results of a phase II randomized, placebo-controlled trial with a re-treatment extension."
11/01/2009 - "Severe cutaneous psoriasis after certolizumab pegol treatment: report of a case."
11/01/2015 - "Certolizumab pegol (CZP) is a PEGylated Fc-free anti-TNF that has been shown clinically to be effective in the treatment of rheumatoid arthritis (RA), skin psoriasis, and PsA. "
03/01/2014 - "The other two TNF inhibitors, golimumab and certolizumab pegol, have shown efficacy against plaque psoriasis in clinical trials of psoriatic arthritis (PsA). "
01/01/2015 - "We report the incidence of tuberculosis (TB) across certolizumab pegol (CZP) clinical trials in rheumatoid arthritis (RA), psoriasis, psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA), before and after the introduction of stricter TB screening. "
|4.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|9.||TNFR-Fc fusion protein (etanercept)
|10.||Antirheumatic Agents (DMARD)
|2.||Renal Dialysis (Hemodialysis)
|4.||Surgical Instruments (Clip)
|5.||Stem Cell Transplantation