neuregulin-4

RefSeq NM_138573 (human); NM_032002.2 (mouse); NM_001191109.1 (rat)

Also Known As:

NRG4 protein, human; Nrg4 protein, mouse; Nrg4 protein, rat; neuregulin 4, human; neuregulin 4, mouse; neuregulin 4, rat

Networked: 18 relevant articles (3 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Farshidi, Hossein: 2 articles (01/2021 - 01/2020)
2.	Farshidi, Narges: 2 articles (01/2021 - 01/2020)
3.	Montazerghaem, Hossein: 2 articles (01/2021 - 01/2020)
4.	Naderi, Nadereh: 2 articles (01/2021 - 01/2020)
5.	Rahimzadeh, Mahsa: 2 articles (01/2021 - 01/2020)
6.	Aktas, Gulali: 2 articles (03/2020 - 10/2019)
7.	Atak, Burcin M: 2 articles (03/2020 - 10/2019)
8.	Duman, Tuba T: 2 articles (03/2020 - 10/2019)
9.	Erkus, Edip: 2 articles (03/2020 - 10/2019)
10.	Savli, Haluk: 2 articles (03/2020 - 10/2019)

Related Diseases

1.	Atherosclerosis 11/01/2022 - "Here we show that BAT-derived neuregulin-4 (Nrg4) ameliorates atherosclerosis in mice. " 01/01/2022 - "The new adipokine, neuregulin-4 (NRG-4), acts as a signaling protein and plays a role in lipogenesis, inflammatory events and atherosclerosis. " 04/01/2022 - "We assessed the effect of oral supplementation with metformin on glycemic control, neuregulin-4 levels and carotid intima media thickness (CIMT) as a marker for subclinical atherosclerosis in adolescents with type 1 diabetes mellitus (T1DM) and microvascular complications. "
2.	Insulin Resistance 10/11/2022 - "Neuregulin-4 (Nrg4) is an adipokine that exerts protective effects against metabolic disorders and insulin resistance. " 04/01/2022 - "Low neuregulin-4 (Nrg-4) levels, an adipokine, are linked to obesity, insulin resistance, impaired glucose tolerance and type 2 diabetes. " 01/01/2019 - "Neuregulin-4 (Nrg4) is a novel adipokine associated with obesity, hyperglycemia, insulin resistance, dislipidemia, inflammation, and oxidative stress in mice and humans. "
3.	Inflammation (Inflammations) 11/02/2023 - "We previously showed that exogenous neuregulin-4 (NRG4) promotes colonocyte survival during cytokine challenge and is protective against acute models of intestinal inflammation. " 01/01/2019 - "Neuregulin-4 (Nrg4) is a novel adipokine associated with obesity, hyperglycemia, insulin resistance, dislipidemia, inflammation, and oxidative stress in mice and humans. "
4.	Type 2 Diabetes Mellitus (MODY) 10/21/2019 - "The aim of the study was to observe the relationship between serum neuregulin-4 levels and diabetes regulation in type 2 diabetes mellitus (T2DM), and to compare neuregulin-4 levels of diabetic subjects with those in healthy controls. " 03/01/2020 - "Is Neuregulin-4 a predictive marker of microvascular complications in type 2 diabetes mellitus?" 10/21/2019 - "Neuregulin-4 is associated with plasma glucose and increased risk of type 2 diabetes mellitus." 04/01/2022 - "Low neuregulin-4 (Nrg-4) levels, an adipokine, are linked to obesity, insulin resistance, impaired glucose tolerance and type 2 diabetes. "
5.	Hypertension (High Blood Pressure) 05/22/2022 - "To explore the myocardial protective effect of Neuregulin-4 (NRG-4) gene expression on spontaneous hypertension (SHR) rats and its mechanism through mediating the activation of the ErbB signaling pathway, this study was conducted. "

Related Drugs and Biologics

1.	Adipokines
2.	Cytokines
3.	Glucose (Dextrose)
4.	EGF Family of Proteins
5.	Interleukin-10 Receptors
6.	Intercellular Signaling Peptides and Proteins (Growth Factors)
7.	Neuregulins
8.	Interleukin-9 (Interleukin 9)
9.	Triglycerides (Triacylglycerol)
10.	Proteins (Proteins, Gene)

Related Therapies and Procedures

1.	Therapeutics
2.	Glycemic Control