novispirin G10

03/01/2007 - "This implicates the potential of P-novispirin G10 as an alternative in future antimicrobial wound care. "
03/01/2007 - "In the infected wound chamber model P-novispirin G10 demonstrated a 4 log(10) reduction in bacterial counts. "
03/01/2007 - "Antimicrobial activity of the recombinant designer host defence peptide P-novispirin G10 in infected full-thickness wounds of porcine skin."
03/01/2007 - "After wound infection had been established (4 days after inoculation), each wound chamber was topically treated with P-novispirin G10, protegrin-1 or carrier control. "
03/01/2007 - "Therefore, the aim of this study was to investigate the antimicrobial activity of proline-novispirin G10 (P-novispirin G10) in vitro and in the infected porcine titanium wound chamber model. "

03/01/2007 - "After wound infection had been established (4 days after inoculation), each wound chamber was topically treated with P-novispirin G10, protegrin-1 or carrier control. "
06/01/2002 - "Antimicrobial peptides such as novispirin G10 may provide a useful alternative or adjunct to standard antibiotic agents in treating burns or other wound infections."

09/01/2005 - "aeruginosa infection, the treated group of rats received novispirin G10 (0.1 mg/ml, 0.1 ml/rat) intratracheally, whereas the control group received vehicle treatment only. "
09/01/2005 - "Effects of intratracheal administration of novispirin G10 on a rat model of mucoid Pseudomonas aeruginosa lung infection."

06/01/2002 - "We tested the in vivo activity of novispirin G10 in rats with an infected, partial-thickness burn that covered 20% of their total body surface area. "
06/01/2002 - "Activity of novispirin G10 against Pseudomonas aeruginosa in vitro and in infected burns."
06/01/2002 - "Antimicrobial peptides such as novispirin G10 may provide a useful alternative or adjunct to standard antibiotic agents in treating burns or other wound infections."

12/01/2003 - "Five hours later, the Klebsiella-infected mice were instilled with saline, tobramycin (1 mg/kg of body weight or 10 mg/kg), novispirin G10 (0.4 mg/kg), or a combination of tobramycin (1 mg/kg) and G10 (0.4 mg/kg). "