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1- ((1- (3- acetoxy- 2,2- dimethylpropyl)- 7- chloro- 5- (2,3- dimethoxyphenyl)- 2- oxo- 1,2,3,5- tetrahydro- 4,1- benzoxazepin- 3- yl)acetyl)piperidine- 4- acetic acid

inhibits squalene synthase; structure in first source
Also Known As:
(1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid; TAK 475; TAK-475; TAK475; lapaquistat
Networked: 5 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Imura, Yoshimi: 2 articles (07/2003 - 04/2003)
2. Ishikawa, Eiichiro: 2 articles (07/2003 - 04/2003)
3. Nishimoto, Tomoyuki: 2 articles (07/2003 - 04/2003)
4. Sugiyama, Yasuo: 2 articles (07/2003 - 04/2003)
5. Amano, Yuichiro: 2 articles (07/2003 - 04/2003)
6. Stein, Evan A: 1 article (05/2011)
7. Pedicano, Jim: 1 article (05/2011)
8. Spezzi, Andrea: 1 article (05/2011)
9. Piper, Edward: 1 article (05/2011)
10. Bays, Harold: 1 article (05/2011)

Related Diseases

1. Dyslipidemias (Dyslipidemia)
2. Atherosclerotic Plaque (Atheroma)
3. Myocardial Infarction
4. Hyperlipidemias (Hyperlipidemia)
5. Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)

Related Drugs and Biologics

1. Farnesyl-Diphosphate Farnesyltransferase (Squalene Synthase)
2. Carbon Monoxide