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ABT 866

an alpha1-adrenoceptor ligand; structure in first source

Also Known As:

ABT-866; ABT866; N-(3-(1H-imidazol-4-ylmethyl)phenyl)ethanesulfonamide

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - ABT 866: 1
Organic Chemicals: 133
- Amides: 2428
  - Sulfonamides: 2809
    - ABT 866: 1
- Sulfur Compounds: 278
  - Sulfones: 534
    - Sulfonamides: 2809
      - ABT 866: 1

Experts

1.	Hirose, Masamichi: 1 article (05/2010)
2.	Matsuo, Kiyoshi: 1 article (05/2010)
3.	Nakada, Tsutomu: 1 article (05/2010)
4.	Nakayama, Jun: 1 article (05/2010)
5.	Yamada, Mitsuhiko: 1 article (05/2010)
6.	Yano, Shiharu: 1 article (05/2010)

Related Diseases

1.

Blepharoptosis (Ptosis, Eyelid)

05/01/2010 - "ABT-866, a selective alpha(1A)-adrenoceptor agonist, increased the upper eyelid contractile force as effectively as phenylephrine in a dose-dependent manner (K(0.5) = 190 nmol), and the contraction continued again for more than 100 min. These results suggest that selective alpha(1A)-adrenoceptor agonists, such as ABT-866, induce the sustained Mueller's muscle contraction and may be useful in pharmacological treatment of blepharoptosis."

Related Drugs and Biologics

1.	Phenylephrine (Neo-Synephrine)