1,4- bis(4'- hydroxystyryl)- 2- methoxybenzene

01/01/2020 - "Golgi-Cox impregnation of neurons combined with methoxy-X04 staining of amyloid plaques is a highly reliable, easy-to-use method for permanent visualization of spines as compared to the technically more sophisticated and less stable fluorescence imaging of spines. "
10/28/2014 - "Methoxy-X04 was used to visualize amyloid deposits in vivo. "
07/01/2004 - "PrP amyloid deposits could also be detected by direct application of methoxy-X04 on cerebellar sections from GSS patients. "
07/01/2004 - "Labeling of PrP amyloid plaques in brains of presymptomatic and symptomatic mice was demonstrated using in vivo transcranial two-photon microscopy after systemic administration of methoxy-X04. "
07/01/2004 - "During real-time imaging, PrP amyloid deposits could be clearly distinguished 15 min after intravenous administration of methoxy-X04. "

01/01/2014 - "Since the need for new markers is high, we prepared methoxy-X04 derivatives and evaluated their potential as imaging agents in Alzheimer's disease pathology. "
01/01/2014 - "Synthesis of methoxy-X04 derivatives and their evaluation in Alzheimer's disease pathology."
12/01/2019 - "Evaluation of the methoxy-X04 derivative BSC4090 for diagnosis of prodromal and early Alzheimer's disease from bioptic olfactory mucosa."

07/01/2004 - "These results suggest that methoxy-X04 or similar derivatives could be used as PET imaging agents to improve the diagnosis of human prion diseases associated with amyloid deposition."
07/01/2004 - "Using methoxy-X04, we investigated whether amyloid-targeting ligands can be also employed for direct imaging of amyloid deposits associated with some prion diseases. "

01/01/2015 - "We herein labeled β-amyloid deposits in a transgenic mouse model of cerebral β-amyloidosis (APPPS1 transgenic mice) with two intraperitoneal injections of the amyloid-binding fluorescent dye methoxy-X04. "