|1.||Looi, Chung Yeng: 2 articles (01/2015 - 01/2013)|
|2.||Arya, Aditya: 2 articles (01/2015 - 01/2013)|
|3.||Mustafa, Mohd Rais: 2 articles (01/2015 - 01/2013)|
|4.||Ananda Sadagopan, Suresh Kumar: 1 article (01/2015)|
|5.||Pandurangan, Ashok Kumar: 1 article (01/2015)|
|6.||Hasanpourghadi, Mohadeseh: 1 article (01/2015)|
|7.||Mohebali, Nooshin: 1 article (01/2015)|
|8.||Karimian, Hamed: 1 article (01/2015)|
|9.||Mohamad, Khalit: 1 article (01/2013)|
|10.||Rai, Nitika: 1 article (01/2013)|
|1.||Breast Neoplasms (Breast Cancer)
01/01/2013 - "To the best of our knowledge, this is the first comprehensive study on cytotoxic and apoptotic mechanism of vernodalin isolated from the Centratherum anthelminticum (L.) seeds in human breast cancer cells. "
01/01/2015 - "Our results suggest that PI3K-Akt/FOXOa pathway is a critical mediator of vernodalin-induced cytotoxicity and this compound could be further developed as a potential chemopreventive or chemotherapeutic agent for breast cancer therapy."
01/01/2015 - "We also corroborated our findings in vivo by showing upregulation of p27Kip1, FOXO3a and decrease in the p-FOXO3a level in vernodalin-treated breast tumor tissue. "
01/01/2015 - "Silencing of FOXO3a protected breast cancer cells against vernodalin induced apoptosis. "
01/01/2015 - "Immunofluorescence, subcellular fractionation and Western blot showed FOXO3a accumulation in the nucleus of breast cancer cells after vernodalin treatment. "
01/01/2013 - "Overall, our data suggest a potential therapeutic value of vernodalin to be further developed as new anti-cancer drug."
01/01/2015 - "The anti-tumor action of vernodalin was further confirmed by examining cell proliferative markers, PCNA and Ki67 in the LA7-induced mammary gland tumor model. "
01/01/2015 - "Our results showed that vernodalin regulates cancer cell apoptosis through activation of FOXO transcription factors and its downstream targets (Bim, p27Kip1, p21Waf1/cip1, cyclin D1, cyclin E) as examined by Western blots. "
|3.||Ovarian Neoplasms (Ovarian Cancer)
|4.||Melanoma (Melanoma, Malignant)
|2.||Cytochromes c (Cytochrome c)
|5.||Proliferating Cell Nuclear Antigen (PCNA)
|6.||Reactive Oxygen Species (Oxygen Radicals)
|7.||Transcription Factors (Transcription Factor)