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mouse CNGRC fusion protein tumor Necrosis Factor-alpha

TNF fused with the C-terminus of CNGRCG

Also Known As:

tumor Necrosis Factor-alpha, CNGRC fusion protein, mouse; NGR-TNF, mouse; NGR-mTNF

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - Tumor Necrosis Factor-alpha: 62515
      - mouse CNGRC fusion protein tumor Necrosis Factor-alpha: 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
- Peptides: 82426
  - Intercellular Signaling Peptides and Proteins: 29768
    - Cytokines: 164289
      - Monokines: 214
        Tumor Necrosis Factor-alpha: 62515
        mouse CNGRC fusion protein tumor Necrosis Factor-alpha: 1
      - Tumor Necrosis Factors: 152
        Tumor Necrosis Factor-alpha: 62515
        mouse CNGRC fusion protein tumor Necrosis Factor-alpha: 1
Biological Factors: 2472
- Intercellular Signaling Peptides and Proteins: 29768
  - Cytokines: 164289
    - Monokines: 214
      - Tumor Necrosis Factor-alpha: 62515
        mouse CNGRC fusion protein tumor Necrosis Factor-alpha: 1
    - Tumor Necrosis Factors: 152
      - Tumor Necrosis Factor-alpha: 62515
        mouse CNGRC fusion protein tumor Necrosis Factor-alpha: 1

Experts

1.	Asperti, Claudia: 1 article (10/2015)
2.	Bordignon, Claudio: 1 article (10/2015)
3.	Mangia, Patrizia: 1 article (10/2015)
4.	Porcellini, Simona: 1 article (10/2015)
5.	Rizzardi, Gian-Paolo: 1 article (10/2015)
6.	Tiziano, Elena: 1 article (10/2015)
7.	Traversari, Catia: 1 article (10/2015)
8.	Valentinis, Barbara: 1 article (10/2015)

Related Diseases

1.

Neoplasms (Cancer)

10/01/2015 - "At molecular level, overexpression of genes involved in vessels normalization was detected only in NGR-mTNF-treated tumors from immunocompetent mice. "
10/01/2015 - "Interestingly, NGR-mTNF-treated tumors from these mice are characterized by CD8+ T cell infiltration. "
10/01/2015 - "At a later stage, NGR-mTNF is able to reduce tumor growth inducing vascular normalization, exclusively when treatment is carried out in the immunocompetent mice. "