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human ETV6-PDGFRB fusion protein

a small proportion of patients with chronic myeloproliferative diseases have constitutive activation of the gene for platelet-derived growth factor receptor beta (PDGFRB), which encodes a receptor tyrosine kinase. The gene is located on chromosome 5q33, and the activation is usually caused by a t(5;12)(q33;p13) translocation associated with an ETV6-PDGFRB fusion gene; has been sequenced
Also Known As:
ETV6-PDGFRB fusion protein, human; ETV6-PDGFRB protein, human
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