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ONYX015 (ONYX-015)

ONYX-015 (CI-1042) is an adenovirus modified selectively to replicate in and kill cells that harbor p53 mutations for the potential treatment of various solid tumors, including head and neck, gastrointestinal and pancreatic tumors
Also Known As:
ONYX-015; CI-1042; CI1042; dl1520
Networked: 132 relevant articles (12 outcomes, 45 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kirn, D: 12 articles (02/2007 - 03/2000)
2. Nemunaitis, J: 6 articles (11/2007 - 08/2000)
3. Randlev, B: 6 articles (03/2005 - 08/2000)
4. Heise, C: 6 articles (01/2002 - 03/2000)
5. Ganly, I: 6 articles (03/2001 - 03/2000)
6. Qian, Cheng: 5 articles (12/2007 - 04/2004)
7. Kirn, David H: 5 articles (11/2007 - 02/2002)
8. Reid, Tony R: 4 articles (08/2015 - 02/2003)
9. Korn, W M: 4 articles (11/2009 - 10/2000)
10. Portella, Giuseppe: 4 articles (10/2008 - 06/2002)

Related Diseases

1. Neoplasms (Cancer)
2. Carcinoma (Carcinomatosis)
3. Prostatic Neoplasms (Prostate Cancer)
4. Head and Neck Neoplasms (Head and Neck Cancer)
5. Colorectal Neoplasms (Colorectal Cancer)

Related Drugs and Biologics

1. Mitoxantrone (Novantrone)
2. Hormones
3. icodextrin (Extraneal)
4. docetaxel (Taxotere)
5. ONYX015 (ONYX-015)
6. Cisplatin (Platino)
7. Fluorouracil (Carac)
8. Tumor Suppressor Protein p14ARF (p14ARF)
9. Mitomycin (Mitomycin-C)
10. Doxorubicin (Adriamycin)

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Drug Therapy (Chemotherapy)
3. Intravenous Infusions
4. Oncolytic Virotherapy
5. Radiotherapy