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N(epsilon)-(malondialdehyde)lysine

Also Known As:

MDA-lys

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675

Experts

1.	Ayala, Victòria: 1 article (06/2005)
2.	Bellmunt, Maria Josep: 1 article (06/2005)
3.	Dalfó, Esther: 1 article (06/2005)
4.	Ferrer, Isidre: 1 article (06/2005)
5.	Pamplona, Reinald: 1 article (06/2005)
6.	Portero-Otín, Manuel: 1 article (06/2005)
7.	Prat, Joan: 1 article (06/2005)

Related Diseases

1.	Atherosclerosis 01/01/1999 - "MDA-lysine epitope (MDA-lys) is closely associated with atherogenesis and was recognized as marker for oxidation. " 01/01/1999 - "The uptake of non-oxidatively modified LDL (acetylated LDL) was sufficient to generate MDA-lys epitope in foam cells, consistent with the hypothesis that atherosclerosis is associated with oxidative events in addition to LDL oxidation. "
2.	Hyperthyroidism 10/01/1999 - "The levels of the glycation product N(epsilon)-fructoselysine (FL) and those of the oxidation products, N(epsilon)-(carboxymethyl)lysine (CML) and malondialdehyde-lysine (MDA-lys), identified by GC/MS in liver proteins, decreased significantly in hyperthyroid rats, as well as (less acutely) in hypothyroid animals. "
3.	Alzheimer Disease (Alzheimer's Disease) 06/03/2005 - "Consequently we analyzed (i) the presence and concentrations of glutamic and aminoadipic semialdehydes, N(epsilon)-(carboxymethyl)-lysine, N(epsilon)-(carboxyethyl)-lysine, and N(epsilon)-(malondialdehyde)-lysine by means of gas chromatography/mass spectrometry, (ii) the biological response through expression of the receptor for advanced glycation end products, (iii) the fatty acid composition in brain samples from Alzheimer disease patients and age-matched controls, and (iv) the targets of N(epsilon)-(malondialdehyde)-lysine formation in brain cortex by proteomic techniques. "

Related Drugs and Biologics

1.	Lysine (L-Lysine)
2.	N(6)-carboxymethyllysine (carboxymethyllysine)
3.	Proteins (Proteins, Gene)
4.	Malondialdehyde (Propanedial)
5.	Fatty Acids (Saturated Fatty Acids)
6.	Epitopes
7.	Receptor for Advanced Glycation End Products
8.	oxidized low density lipoprotein
9.	N(6)-(1-carboxyethyl)lysine
10.	fructosyl-lysine