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ZD0947
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyridines: 88
Dihydropyridines: 214
ZD0947: 1
Experts
1.
Abdel-Karim, Aly M
: 1 article (08/2002)
2.
Bialecki, Russell A
: 1 article (08/2002)
3.
Elhilali, Mostafa M
: 1 article (08/2002)
Related Diseases
1.
Overactive Urinary Bladder (Overactive Bladder)
08/01/2002 - "
ZD6169 and ZD0947 are effective treatment for detrusor hyperreflexia after spinal cord injury and they may provide alternative treatment options for overactive bladder.
"
2.
Spinal Cord Injuries (Spinal Cord Injury)
08/01/2002 - "
ZD6169 and ZD0947 are effective treatment for detrusor hyperreflexia after spinal cord injury and they may provide alternative treatment options for overactive bladder.
"
08/01/2002 - "
We tested the efficacy of the 2 adenosine triphosphate dependent K channel openers ZD6169 and ZD0947 on detrusor hyperreflexia after spinal cord injury in rats.
"
3.
Abnormal Reflex (Hyperreflexia)
08/01/2002 - "
All animals that received a dose of 3 mg./kg. ZD0947 daily for 1 week showed no detrusor hyperreflexia with a mean bladder capacity of 2.7 +/- 1.8 ml. and mean voiding pressure of 34 +/- 8.5 cm. water, while at 0.3 mg./kg. daily 83% showed no detrusor hyperreflexia with a mean bladder capacity of 2.5 +/- 2.0 ml. and a mean voiding pressure of 41.5 +/- 13.8 cm. water.
"
08/01/2002 - "
ZD6169 and ZD0947 are effective treatment for detrusor hyperreflexia after spinal cord injury and they may provide alternative treatment options for overactive bladder.
"
08/01/2002 - "
We tested the efficacy of the 2 adenosine triphosphate dependent K channel openers ZD6169 and ZD0947 on detrusor hyperreflexia after spinal cord injury in rats.
"
Related Drugs and Biologics
1.
Adenosine Triphosphate (ATP)
2.
Zeneca ZD 6169