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kalopanax saponin A

Also Known As:
kalopanaxsaponin A; sapindoside A
Networked: 9 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Chung, Won-Yoon: 2 articles (01/2012 - 07/2009)
2. Hwang, Young Sun: 2 articles (01/2012 - 07/2009)
3. Park, Kwang-Kyun: 2 articles (01/2012 - 07/2009)
4. Park, Hee-Juhn: 2 articles (07/2009 - 11/2008)
5. Cheng, Yu-Liang: 1 article (11/2021)
6. Guo, Ya-Hui: 1 article (11/2021)
7. Wei, Min-Ping: 1 article (11/2021)
8. Xie, Yun-Fei: 1 article (11/2021)
9. Yao, Wei-Rong: 1 article (11/2021)
10. Yu, Hang: 1 article (11/2021)

Related Diseases

1. Colitis
2. Neoplasms (Cancer)
03/01/2001 - "These results indicated that kalopanaxsaponin A has potential anti-tumor applications."
03/01/2001 - "Kalopanaxsaponin A is a basic saponin structure for the anti-tumor activity of hederagenin monodesmosides."
10/01/2016 - "Clematoside S, sapindoside B, kalopanax saponin A, and koelreuteria saponin A exhibited cytotoxicity against all of the test cancer cell lines with IC50 values in the range of 1.88-27.20 μM, while clematangoticoside D and F showed selective cytotoxicity against SGC-7901 with IC50 values of 24.22 and 21.35 μM, respectively. "
07/01/2023 - "This paper is the first comprehensive review of its chemistry, pharmacology, and toxicity for more than half a century (1966-2022), in which the chemical studies include triterpenoids & saponins (86 compounds), and phenylpropanoids (26 compounds), involving 46 new structures and one biomarker-triterpenoid saponin (Kalopanaxsaponin A); According to the number of literature, the pharmacological effects and mechanisms are systematically divided into five aspects, such as: anti-inflammatory, anti-tumor, antioxidant, antifungal and anti-diabetic, etc., covering its toxicological progress. "
03/01/2001 - "Among glycosides of hederagenin, disaccharide (kalopanaxsaponin A, commonly also called alpha-hederin), trisaccharide (kalopanaxsaponin I), and tetrasaccharide (sapindoside C) showed significant cytotoxicity on several types of tumor cells, while hederagenin itself exhibited only weak cytotoxicity and its monosaccharide (delta-hederin) was non-cytotoxic. "
3. Squamous Cell Carcinoma of Head and Neck
4. Mitochondrial Diseases (Mitochondrial Disease)
5. Lewis Lung Carcinoma

Related Drugs and Biologics

1. Saponins
2. Matrix Metalloproteinase 9 (Gelatinase B)
3. Triterpenes
4. phorbol
5. Biomarkers (Surrogate Marker)
6. Antioxidants
7. Caspase 8 (Caspase-8)
8. Reactive Oxygen Species (Oxygen Radicals)
9. NF-kappa B (NF-kB)
10. Cytokines