TNF-selectokine

a TNF fusion protein, which is a homo-trimeric molecule comprised of a single chain antibody (scFv) targeting module, a trimerization domain and TNF

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Banerjee, Debola: 1 article (06/2002)
2.	Gerlach, Elke: 1 article (06/2002)
3.	Gerspach, Jeannette: 1 article (06/2002)
4.	Moosmayer, Dieter: 1 article (06/2002)
5.	Pfizenmaier, Klaus: 1 article (06/2002)
6.	Wüest, Thomas: 1 article (06/2002)

Related Diseases

1.	Neoplasms (Cancer) 06/20/2002 - "TNF-Selectokine: a novel prodrug generated for tumor targeting and site-specific activation of tumor necrosis factor." 06/20/2002 - "To restrict TNF activity to the tumor, a prototype of a TNF-Selectokine prodrug was constructed by insertion of a TNFR1 fragment, separated from TNF by a protease-sensitive linker. "

Related Drugs and Biologics

1.	Type I Tumor Necrosis Factor Receptors
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Prodrugs
4.	Peptide Hydrolases (Proteases)