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human AML1-MDS1-EVI1 fusion protein

leukemia-associated fusion gene AML1/MDS1/EVI1 (AME) encodes a chimeric transcription factor that results from the (3;21)(q26;q22) translocation; this translocation is observed in patients with therapy-related myelodysplastic syndrome (MDS), with chronic myelogenous leukemia during the blast crisis (CML-BC), and with de novo or therapy-related acute myeloid leukemia (AML)
Also Known As:
AML1-MDS1-EVI1 fusion protein, human; AML1-MDS1-EVI1 protein, human
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