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nitrophenyl N-oluenesulfonyl-aminoisobutyrate
structure in first source
Also Known As:
NTS-AB; ortho-nitrophenyl Nalpha-para-toluenesulfonyl-alpha-aminoisobutyrate
Networked:
1
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Carboxylic Acids: 973
Acyclic Acids
Butyrates: 2613
Isobutyrates: 2
Aminoisobutyric Acids
nitrophenyl N-oluenesulfonyl-aminoisobutyrate: 1
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Branched-Chain Amino Acids: 2289
Aminoisobutyric Acids
nitrophenyl N-oluenesulfonyl-aminoisobutyrate: 1
Aminobutyrates: 1253
Aminoisobutyric Acids
nitrophenyl N-oluenesulfonyl-aminoisobutyrate: 1
Related Diseases
1.
Neoplasms (Cancer)
12/01/2023 - "
In addition, Ir Nts-Ab targets CSCs and normal cancer cells with near infrared II-region photothermal therapy (NIR-II PTT), and is easily taken up by CSCs due to recognition of the CD44 proteins.
"
12/01/2023 - "
Additionally, Ir Nts-Ab achieved the eradication of CSCs by PTT, and eliminated reactive oxygen species to decrease the inflammatory response, resulting in reduced tumor metastasis, which was promising for the cure of solid tumors in the clinics.
"
12/01/2023 - "
Herein, we developed a CD44 antibody modified iridium nanosheet with enzyme-like activity (defined as Ir Nts-Ab) that effectively eradicates CSCs for cancer therapy.
"
12/01/2023 - "
Ir Nts-Ab with catalase-like activity could inhibit HIF-1α by producing oxygen, thus effectively reducing the proportion of CSCs and inhibiting tumor metastasis.
"
12/01/2023 - "
We observe that Ir Nts-Ab can enrich tumor tissues to remove excessive reactive oxygen species and produce oxygen, thus alleviating hypoxia and the inflammatory TME to reduce the proportion of CSCs and inhibit metastasis.
"
2.
Neoplasm Metastasis (Metastasis)
12/01/2023 - "
Additionally, Ir Nts-Ab achieved the eradication of CSCs by PTT, and eliminated reactive oxygen species to decrease the inflammatory response, resulting in reduced tumor metastasis, which was promising for the cure of solid tumors in the clinics.
"
12/01/2023 - "
Ir Nts-Ab with catalase-like activity could inhibit HIF-1α by producing oxygen, thus effectively reducing the proportion of CSCs and inhibiting tumor metastasis.
"
12/01/2023 - "
We observe that Ir Nts-Ab can enrich tumor tissues to remove excessive reactive oxygen species and produce oxygen, thus alleviating hypoxia and the inflammatory TME to reduce the proportion of CSCs and inhibit metastasis.
"
3.
Hypoxia (Hypoxemia)
12/01/2023 - "
We observe that Ir Nts-Ab can enrich tumor tissues to remove excessive reactive oxygen species and produce oxygen, thus alleviating hypoxia and the inflammatory TME to reduce the proportion of CSCs and inhibit metastasis.
"
Related Drugs and Biologics
1.
Reactive Oxygen Species (Oxygen Radicals)
2.
Proteins (Proteins, Gene)
3.
Oxygen (Dioxygen)
4.
Iridium
5.
Enzymes
6.
Catalase
Related Therapies and Procedures
1.
Therapeutics
2.
Photothermal Therapy