altholactone

02/07/2017 - "The objective of this study was to elucidate the mechanism of action of altholactone against prostate cancer DU145 cells and to evaluate whether its effects are mediated by inhibition of NF-κB and STAT3 activity. "
02/07/2017 - "Altholactone Inhibits NF-κB and STAT3 Activation and Induces Reactive Oxygen Species-Mediated Apoptosis in Prostate Cancer DU145 Cells."

06/01/2014 - "In the present study, we characterized the effect of altholactone on cell growth and apoptosis in bladder cancer T24 cells. "
06/01/2014 - "Taken together, our data demonstrate that altholactone induces ROS-dependent apoptosis in T24 cells via a novel mechanism involving inhibition of Akt and provide the rationale for further in vivo and preclinical investigation of altholactone against bladder cancer. "
06/01/2014 - "However, no prior research has been conducted to demonstrate the antiproliferative potential of altholactone on bladder cancer. "
06/01/2014 - "Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression."

06/01/2014 - "Altholactone, isolated from Goniothalamus sp., has been reported to inhibit the growth of various types of cancer cells. "
05/01/2013 - "These unique properties of altholactone suggest a potential for cancer chemotherapy."
05/01/2013 - "In this work, altholactone isolated from Goniothalamus macrophyllus was investigated for its cytotoxicity, apoptosis signalling and the expression of cancer-related genes in the cervical carcinoma HeLa cells. "
05/01/2013 - "Role of altholactone in inducing type II apoptosis signalling pathway and expression of cancer-related genes in cervical carcinoma HeLa cell line."
07/01/2020 - "Such activity of 3-fluorobenzoate derivative of altholactone should be further explored for the development of an anti-cancer drug for CCA."

06/01/2012 - "These results indicate that altholactone induces selective cytotoxicity against colon carcinoma cells and warrants further clinical evaluation."
05/01/2013 - "In this work, altholactone isolated from Goniothalamus macrophyllus was investigated for its cytotoxicity, apoptosis signalling and the expression of cancer-related genes in the cervical carcinoma HeLa cells. "
05/01/2013 - "Role of altholactone in inducing type II apoptosis signalling pathway and expression of cancer-related genes in cervical carcinoma HeLa cell line."

06/01/2014 - "Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression."