UDP-GlcNAc GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase

11/16/2017 - "In this study, we found that the reduced expression of core 3 synthase correlated with metastasis to lymph nodes and distant organs, resulting in poor prognosis for colorectal cancer (CRC) patients. "
12/15/2013 - "Orthotopic injection of FG cells expressing core 3 synthase into the pancreas of nude mice produced significantly smaller tumors and decreased metastasis to the surrounding tissues compared to vector control FG cells. "
12/15/2013 - "Expression of core 3 synthase in human pancreatic cancer cells suppresses tumor growth and metastasis."
05/01/2006 - "[Core 3 synthase is down-regulated in colon carcinoma and suppresses the cancer metastasis]."

11/16/2017 - "In this study, we found that the reduced expression of core 3 synthase correlated with metastasis to lymph nodes and distant organs, resulting in poor prognosis for colorectal cancer (CRC) patients. "

12/15/2013 - "The addition of a GlcNAc residue by core 3 synthase leads to the extension of the tumor-associated Tn structure on MUC1. "
12/15/2013 - "We determined that pancreatic tumors and tumor cell lines have lost expression of core 3 synthase. "
12/15/2013 - "Orthotopic injection of FG cells expressing core 3 synthase into the pancreas of nude mice produced significantly smaller tumors and decreased metastasis to the surrounding tissues compared to vector control FG cells. "
03/22/2005 - "Tissue specimens from a familial adenomatous polyposis patient showed a clear correlation between the down-regulation of beta3Gn-T6 expression and the degree of dysplasia/neoplasia. "
12/15/2013 - "Core 3-derived glycans, a major type of O-glycan expressed by normal epithelial cells of the gastrointestinal tract, are downregulated during malignancy because of loss of expression of functional β3-N-acetylglucosaminyltransferase-6 (core 3 synthase). "

03/22/2005 - "Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells."
05/01/2006 - "[Core 3 synthase is down-regulated in colon carcinoma and suppresses the cancer metastasis]."

11/01/2021 - "Association between the expression of core 3 synthase and survival outcomes of patients with cholangiocarcinoma."