|1.||Zi, Xiaolin: 5 articles (01/2013 - 10/2010)|
|2.||Akhtar, M Nadeem: 3 articles (07/2015 - 01/2013)|
|3.||Abu, Nadiah: 3 articles (07/2015 - 01/2013)|
|4.||Alitheen, Noorjahan Banu: 3 articles (07/2015 - 01/2013)|
|5.||Omar, Abdul Rahman: 3 articles (07/2015 - 01/2013)|
|6.||Abdullah, Mohd Puad: 3 articles (07/2015 - 01/2013)|
|7.||Yeap, Swee Keong: 3 articles (07/2015 - 01/2013)|
|8.||Guo, Yi: 3 articles (01/2013 - 07/2012)|
|9.||Wang, Sheng-Yang: 3 articles (04/2012 - 07/2010)|
|10.||Hoang, Bang H: 2 articles (01/2013 - 07/2012)|
10/01/2012 - "Flavokawain B (FKB) possesses strong anti-neoplastic activity against many cancer cells. "
04/01/2012 - "The induction of cell cycle arrest and apoptosis by flavokawain B may provide a pivotal mechanism for its cancer chemopreventive action."
12/01/2011 - "Flavokawain B induces apoptosis of human oral adenoid cystic cancer ACC-2 cells via up-regulation of Bim and down-regulation of Bcl-2 expression."
01/01/2012 - "The kava root extract and flavokawain B reduce tumor growth, AR expression in tumor tissues and levels of serum PSA in the patient-derived PCa xenograft models. "
01/01/2013 - "Flavokawain B (FKB), a kava extract, has been reported to have significant anti-tumor effects on several carcinoma cell lines both in vitro and in vivo. "
|2.||Prostatic Neoplasms (Prostate Cancer)
10/15/2010 - "We have shown that flavokawain B (FKB), a kava chalcone, is about 4- to 12-fold more effective in reducing the cell viabilities of androgen receptor (AR)-negative, HRPC cell lines DU145 and PC-3 than AR-positive, hormone-sensitive prostate cancer cell lines LAPC4 and LNCaP, with minimal effect on normal prostatic epithelial and stromal cells. "
10/15/2010 - "Flavokawain B, a kava chalcone, induces apoptosis via up-regulation of death-receptor 5 and Bim expression in androgen receptor negative, hormonal refractory prostate cancer cell lines and reduces tumor growth."
|3.||Mouth Neoplasms (Oral Cancer)
|4.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
04/01/2012 - "In the present study, we have investigated the antiproliferative and apoptotic effect of flavokawain B (5-20 μg/ml; 17.6-70.4 μM) against human squamous carcinoma (KB) cells. "
04/01/2012 - "Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo."
01/01/2013 - "Flavokawain B also exerts antinociceptive effects as well as anti-inflammation properties. "
07/01/2015 - "Flavokawain A and flavokawain B are known to possess potential anti-inflammation and anti-cancer activities. "
06/01/2014 - "4-Hydroxyderricin (4HD), xanthoangelol (XAG), cardamonin (CAR) and flavokawain B (FKB) are chalcones that have exhibited various biological effects against obesity, inflammation, and diabetes; however, little is known about the inhibitory effects of these chalcones on fatty liver disease. "
|3.||Androgen Receptors (Androgen Receptor)
|5.||TNF-Related Apoptosis-Inducing Ligand Receptors
|6.||p38 Mitogen-Activated Protein Kinases
|8.||Matrix Metalloproteinase 1 (Interstitial Collagenase)
|9.||Matrix Metalloproteinase 9 (Gelatinase B)
|10.||Urokinase-Type Plasminogen Activator (Urokinase)
|1.||Heterologous Transplantation (Xenotransplantation)