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Dermatophagoides pteronyssinus antigen p 2

a 15 kD protein excreted in the feces by house dust mites Dermatophagoides pteronyssinus; has three intramolecular disulfide bonds; encoded by DERP2 gene; a group 2 Dermatophagoides allergen
Also Known As:
Der p 2; Der p 2 allergen; Der p II; Der p II allergen; mite allergen Der p 2; mite group 2 allergen Der p 2
Networked: 57 relevant articles (1 outcomes, 13 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Tsai, Jaw-Ji: 5 articles (01/2015 - 10/2005)
2. Liao, En-Chih: 4 articles (01/2015 - 04/2013)
3. Chen, Kuan-Wei: 3 articles (07/2015 - 05/2008)
4. Vrtala, Susanne: 3 articles (07/2015 - 05/2008)
5. Yu, Sheng-Jie: 3 articles (01/2015 - 10/2014)
6. Chua, K Y: 3 articles (02/2009 - 03/2000)
7. Liao, En Chih: 2 articles (09/2015 - 05/2015)
8. Tsai, Jaw Ji: 2 articles (09/2015 - 05/2015)
9. Chang, Ching Yun: 2 articles (09/2015 - 05/2015)
10. Valent, Peter: 2 articles (08/2012 - 05/2008)

Related Diseases

1. Mite Infestations (Mange)
2. Asthma (Bronchial Asthma)
3. Hypersensitivity (Allergy)
4. Inflammation
5. Rhinitis
04/05/2005 - "An estimated 79.2% patients with asthma, wheezing and/or rhinitis suffer from Dermatophagoides pteronyssinus group 2 (Der p 2) allegen. "
05/01/1992 - "SIs were compared between different clinical groups of patients, and patients with asthma had significantly higher values to both Der p I and Der p II than patients with rhinitis alone (17.0 +/- 5.4 versus 5.7 +/- 1.0 for Der p I, p less than 0.05; 14.3 +/- 6.8 versus 5.0 +/- 1.0 for Der p II, p less than 0.05)."
11/01/2003 - "The sensitization profile of rhinitis subjects to the dust mite allergens used in this study was as follows: Blo t extract positive: 91/124 (73%); Blo t 5 positive: 62/124 (50%); Der p extract positive: 61/124 (49%); Der p 1 positive: 53/124 (43%); Der p 2 positive: 45/124 (36%). "
08/01/1998 - "In patients with either rhinitis or asthma, the reactivity to Der p 5 and 7 was significantly lower than to Der p 2. However, in patients with combined disease, the positivity to the minor allergens was almost as high as that to Der p 2. These results raise the question of whether patients with combined allergic rhinitis and asthma, when compared to those with either of these diseases alone, are predisposed to react to a wider range of mite allergens, or, inversely, whether patients who respond to the minor allergens are more susceptible to suffering the combined disease."
09/01/2002 - "Use of a chimeric ELISA to investigate immunoglobulin E antibody responses to Der p 1 and Der p 2 in mite-allergic patients with asthma, wheezing and/or rhinitis."

Related Drugs and Biologics

1. Allergens
2. DNA (Deoxyribonucleic Acid)
3. Dermatophagoides pteronyssinus antigen p 1
4. Immunoglobulin E (IgE)
5. Immunoglobulin G (IgG)
6. Antibodies
7. Peptides
8. P-2 (P 2)
9. Dust (House Dust)
10. Antigens

Related Therapies and Procedures

1. Immunotherapy