|1.||Reginato, Mauricio J: 4 articles (05/2015 - 06/2011)|
|2.||Love, Dona C: 4 articles (10/2012 - 08/2002)|
|3.||Hanover, John A: 4 articles (10/2012 - 08/2002)|
|4.||Lynch, Thomas P: 3 articles (06/2014 - 06/2011)|
|5.||Slawson, Chad: 3 articles (01/2013 - 09/2005)|
|6.||Seagroves, Tiffany N: 2 articles (05/2015 - 06/2014)|
|7.||Schwab, Luciana P: 2 articles (05/2015 - 06/2014)|
|8.||Vocadlo, David J: 2 articles (05/2015 - 06/2014)|
|9.||Sodi, Valerie L: 2 articles (05/2015 - 06/2014)|
|10.||Marsh, Susan A: 2 articles (11/2014 - 04/2014)|
|1.||Breast Neoplasms (Breast Cancer)
05/01/2015 - "mTOR/MYC Axis Regulates O-GlcNAc Transferase Expression and O-GlcNAcylation in Breast Cancer."
12/20/2013 - "Previous studies have shown that increased levels of global O-GlcNAcylation and O-GlcNAc transferase (OGT) are linked to the incidence of metastasis in breast cancer patients, but the molecular basis behind this is not fully known. "
05/13/2010 - "We discovered that breast cancer cells upregulate the HBP, including increased O-GlcNAcation and elevated expression of O-GlcNAc transferase (OGT), which is the enzyme catalyzing the addition of O-GlcNAc to proteins. "
05/13/2010 - "Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1."
|2.||Alzheimer Disease (Alzheimer's Disease)
10/01/2013 - "To study the effects of Xixin decoction (XXD) on O-GlcNAc transferase (OGT) and O-GlcNAc glycosidase in O-GlcNAc glycosylation of tau proteins in the brain of rats with sporadic Alzheimer's disease (SAD) and explore the possible mechanism. "
06/01/2012 - "Dysregulation of O-GlcNAc modification catalyzed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) contributes to the etiology of chronic diseases of aging, including cancer, cardiovascular disease, type 2 diabetes, and Alzheimer's disease. "
|3.||Neoplasm Metastasis (Metastasis)
|4.||Squamous Cell Carcinoma (Epidermoid Carcinoma)
07/01/2012 - "The aim of this present study was to explore the expression and clinical significance of O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) and enzymatic O-linked glycosylation (O-GlcNAcation) through the addition of O-linked-β-N-acetylglucosamine in esophageal squamous cell carcinoma. "
12/01/2015 - "Similarly, elevated protein O-GlcNAcylation and O-GlcNAc transferase (OGT) are detected in various cancers and serve as attractive novel cancer-specific therapeutic targets. "
05/01/2015 - "Multiple tumor types contain elevated total O-GlcNAcylation, in part, by increasing O-GlcNAc transferase (OGT) levels, the enzyme that catalyzes this modification. "
06/01/2011 - "O-GlcNAc transferase: a sweet new cancer target."
06/05/2014 - "Cancer cells elevate total O-GlcNAcylation by increasing O-GlcNAc transferase (OGT) and/or decreasing O-GlcNAcase (OGA) levels. "
01/01/2014 - "However, it remains unclear how O-GlcNAcylation and O-GlcNAc cycling enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), affect the development of cancer in animal models. "
|2.||tau Proteins (tau Protein)
|4.||Proteins (Proteins, Gene)
|6.||Small Interfering RNA (siRNA)
|7.||Proteasome Endopeptidase Complex (Proteasome)
|8.||Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
|9.||1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
|10.||Uridine Diphosphate (UDP)