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11-keto-boswellic acid

Also Known As:

11-keto-beta-boswellic acid

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - 11-keto-boswellic acid: 8

Experts

1.	Zhu, Yue: 2 articles (03/2020 - 10/2019)
2.	Jing, Yongkui: 2 articles (10/2018 - 01/2017)
3.	Li, Kun: 2 articles (10/2018 - 01/2017)
4.	Liu, Dan: 2 articles (10/2018 - 01/2017)
5.	Zhao, Linxiang: 2 articles (10/2018 - 01/2017)
6.	Barthel, Alexander: 2 articles (07/2015 - 09/2010)
7.	Csuk, René: 2 articles (07/2015 - 09/2010)
8.	Duan, Jinao: 1 article (03/2020)
9.	Gao, Rumeng: 1 article (03/2020)
10.	Miao, Xiaodong: 1 article (03/2020)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 10/15/2018 - "Design, synthesis and biological evaluation of ring A modified 11-keto-boswellic acid derivatives as Pin1 inhibitors with remarkable anti-prostate cancer activity." 01/27/2017 - "Design and synthesis of novel 2-substituted 11-keto-boswellic acid heterocyclic derivatives as anti-prostate cancer agents with Pin1 inhibition ability."
2.	Neoplasms (Cancer) 09/01/2010 - "An endoperoxide was synthesized starting from 11-keto-beta-boswellic acid and screened for antitumor activity in a panel of 15 human cancer cell lines by an SRB assay. " 06/01/2008 - "Boswellic acids (BA), a natural mixture isolated from oleo gum resin of Boswellia serrata comprised of four major pentacyclic triterpene acids: beta-boswellic acid (the most abundant), 3-acteyl-beta-boswellic acid, 11-keto-beta-boswellic acid, and 3-acetyl-11-keto-beta-boswellic acid, is reported to be effective as anti-inflammatory, immunomodulatory, anti-tumor, anti-asthmatic and in Chron's disease. "
3.	Multiple Myeloma 03/23/2020 - "RXC, MYC significantly inhibited the proliferation of U266 cells at dose of 25-400 μg/mL, YDC and YDS at the dose of 12.5-400 μg/mL. 3-O-acetyl-α-boswellic acid, 3-acetyl-11 keto-boswellic acid and 11-keto-boswellic acid had the most significant anti- multiple myeloma activities in the 10 compounds investigated, therefore these 3 compounds were selected as representatives for Elisa assay and western blotting experiments. "
4.	Leukemia 01/01/2000 - "Addition of pure beta-boswellic acid, 3-O-acetyl-beta-boswellic acid, 11-keto-beta-boswellic acid or 3-O-acetyl-11-keto-beta-boswellic acid to human leukemia HL-60 cell culture inhibited DNA synthesis in HL-60 cells in a dose-dependent manner with IC50 values ranging from 0.6 to 7.1 microM. "
5.	Uterine Cervical Neoplasms (Cancer of the Cervix) 07/15/2015 - "11-Keto-boswellic acid derived amides and monodesmosidic saponins induce apoptosis in breast and cervical cancers cells."

Related Drugs and Biologics

1.	Acids
2.	boswellic acid
3.	Anti-Asthmatic Agents (Antiasthmatic Drugs)
4.	Triterpenes
5.	Saponins
6.	DNA (Deoxyribonucleic Acid)
7.	Amides
8.	3-O-acetyl-beta-boswellic acid