|1.||Villetti, Gino: 2 articles (08/2006 - 05/2004)|
|2.||Cassano, Tommaso: 1 article (10/2007)|
|3.||Cuomo, Vincenzo: 1 article (10/2007)|
|4.||Steardo, Luca: 1 article (10/2007)|
|5.||Castrignanò, Silvia: 1 article (10/2007)|
|6.||Trabace, Luigia: 1 article (10/2007)|
|7.||Colaianna, Marilena: 1 article (10/2007)|
|8.||Giustino, Arcangela: 1 article (10/2007)|
|9.||Amoroso, Salvatore: 1 article (10/2007)|
|10.||Ghidini, Eleonora: 1 article (08/2006)|
|1.||Amnesia (Dissociative Amnesia)
|2.||Alzheimer Disease (Alzheimer's Disease)
10/01/2007 - "Taken together, these findings suggest that ganstigmine appears to be a suitable candidate for the treatment of the cholinergic deficit in patients with Alzheimer's disease."
05/01/2003 - "First clinical evaluation of ganstigmine in patients with probable Alzheimer's disease."
05/01/2003 - "The objective of this study was to evaluate the safety, tolerability, maximum tolerated dose, pharmacokinetics, and pharmacodynamics of five fixed doses of ganstigmine (CHF 2819) in patients with probable Alzheimer's disease (AD). "
05/01/2004 - "In this article, we examined whether and how ganstigmine might prevent or rescue the neurodegenerative phenotype in AD11 antinerve growth factor (anti-NGF) mice, a transgenic model for Alzheimer's disease. "
01/01/2003 - "In order to deepen the understanding of the metabolism of Ganstigmine, a new acetylcholinesterase inhibitor under evaluation for the treatment of Alzheimer's disease, samples obtained by incubating the drug with female rat hepatocytes were investigated by low-resolution liquid chromatography/tandem mass spectrometry (LC/MS/MS). "
08/01/2003 - "Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells."
08/01/2003 - "We have investigated the effect of ganstigmine (CHF2819), a novel geneserine derived acetylcholinesterase (AChE) inhibitor, on the expression and metabolism of the amyloid precursor protein (APP) in neuroblastoma cell line SH-SY5Y. "
|4.||Acetylcholine (Acetylcholine Chloride)
|6.||Nerve Growth Factor (NGF)
|7.||Amyloid (Amyloid Fibrils)