|1.||Zhang, Chao: 2 articles (12/2015 - 11/2013)|
|2.||Zhou, Sheng: 2 articles (12/2015 - 11/2013)|
|3.||Xu, Li-Qiang: 1 article (12/2015)|
|4.||Chen, Guang: 1 article (12/2015)|
|5.||Liao, Yong-de: 1 article (12/2015)|
|6.||Wei, Yan-Hong: 1 article (12/2015)|
|7.||Yu, Li: 1 article (12/2015)|
|8.||Ju, Sheng: 1 article (12/2015)|
|9.||Liu, Zhao-Guo: 1 article (12/2015)|
|10.||Tang, He-Xiao: 1 article (12/2015)|
05/02/2014 - "In summary, the present study shows that the combination of AG1024 with paclitaxel inhibited model cancer cell proliferation, suggesting a new use of paclitaxel-based chemotherapy for cancer control."
03/15/2003 - "The tyrphostin AG1024 accelerates the degradation of phosphorylated forms of retinoblastoma protein (pRb) and restores pRb tumor suppressive function in melanoma cells."
11/15/2013 - "Tumor-bearing mice were divided into seven groups: 17β-estradiol (E2), E2+fulvestrant (Ful; estrogen inhibitor), IGF-1, IGF-1+AG1024 (IGF-1 inhibitor), E2+IGF-1, E2+IGF-1+Ful+AG1024 and control groups. "
03/15/2003 - "AG1024 inhibited the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway and restored pRb tumor suppressive function. "
01/01/2014 - "Cetuximab, a humanized anti-EGF receptor monoclonal antibody used for the treatment of cancer, completely inhibited EGF-induced BRET, and the tyrosine kinase inhibitor tyrphostine AG1024 inhibited insulin effect on PIP3 production. "
|2.||Osteosarcoma (Osteogenic Sarcoma)
|3.||Muscular Atrophy (Muscle Atrophy)
10/31/2010 - "IGF 1 increased the expression of p-Akt, but such effects were prevented by AG1024 resulting in muscle atrophy and poor motor function. "
10/31/2010 - "In the second part of the study, rats were assigned to sham control, ischemic control, ischemia with IGF 1, or with IGF 1 receptor inhibitor (AG1024) injection groups to determine the specificity of IGF 1 on preventing muscle atrophy after brain ischemia. "
|4.||Lung Neoplasms (Lung Cancer)
12/01/2015 - "This study aimed to investigate the effects of IGF-1R and its inhibitor, AG1024, on the progression of lung cancer. "
12/01/2015 - "It was concluded that IGF-1 and IGF inhibitor AG1024 promotes lung cancer progression. "
12/01/2015 - "Effects of insulin-like growth factor 1 receptor and its inhibitor AG1024 on the progress of lung cancer."
|1.||IGF Type 1 Receptor (IGF 1 Receptor)
|4.||salicylhydroxamic acid (SHAM)
|6.||Protein-Tyrosine Kinases (Tyrosine Kinase)
|8.||Insulin-Like Growth Factor I (IGF-1)
|10.||Mitogen-Activated Protein Kinase 1 (p42 MAP Kinase)
|1.||Drug Therapy (Chemotherapy)